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| Number | Title | Issue Date |
| 5147655 | Oral composition containing particles comprising an active substance An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance, the particles being combined with one or more gelling or swe... | 09/15/1992 |
| 4806471 | Plasmids with conditional uncontrolled replication behavior Plasmids useful as cloning vectors carrying an inserted regulatable promoter, transcription from the promoter regulating plasmid replication. Increased transcription leads to a substantially increased or uncontrolled plasmid copy number when host microorg... | 02/21/1989 |
| 4760022 | Stabilized plasmids Plasmids which are in themselves unstably inherited or which have become unstable due to the insertion of a DNA fragment comprising one or more genes not naturally related to the plasmid are stablized by means of a partitioning function exerted by a par r... | 07/26/1988 |
| 4716041 | Diffusion coated multiple-units dosage form In an oral pharmaceutical controlled release multiple-units formulation, individual units containing an active substance are coated with a substantially water-insoluble, but water-diffusible controlled release coating which includes (1) an inner film laye... | 12/29/1987 |
| 4713248 | Diffusion coated multiple-units dosage form In an oral pharmaceutical controlled release multiple-units formulation, individual units containing an active substance are coated with a substantially water-insoluble, but water-diffusible controlled release coating which includes (1) an inner film laye... | 12/15/1987 |
| 4657755 | Composition and method for investigating alimentary functions Enterically administrable diagnostic compositions for investigating alimentary functions comprising multiple units of a size of at the most 5 mm, preferably between 0.5 and 1.3 mm, in particular between 0.7 and 1.0 mm, each unit comprising a tracer substa... | 04/14/1987 |
| 4606909 | Pharmaceutical multiple-units formulation A pharmaceutical oral controlled release multiple-units formulation in which individual units comprise cross-sectionally substantially homogeneous cores containing particles of a sparingly soluble active substance, the cores being coated with a coating wh... | 08/19/1986 |
| 4574080 | Combination formulation A pharmaceutical oral controlled release multiple-units formulation is prepared by mixing units containing an active substance and coated with a substantially water-insoluble, but water diffusable controlled release coating with particles of an active sub... | 03/04/1986 |
| 4572833 | Method for preparing a pharmaceutical controlled release composition A pharmaceutical oral multiple-units composition with controlled release, in which the individual units are coated units of an active substance, e.g. potassium chloride, which is subject to controlled release in consequence of the units being coated with ... | 02/25/1986 |
| 4499189 | Bacteria carrying plasmid having temperature dependent plasmid copy number Gene products of plasmid DNA, such as proteins, are prepared in high yields by cultivating bacteria carrying a plasmid which shows a controlled constant plasmid copy number at one temperature and a much higher or totally uncontrolled copy number at a diff... | 02/12/1985 |
| 4495287 | Process for producing gene products of plasmid having temperature dependent plasmid copy number Gene products of plasmid DNA, such as proteins, are prepared in high yields by cultivating bacteria carrying a plasmid which shows a controlled constant plasmid copy number at one temperture and a much higher or totally uncontrolled copy number at a diffe... | 01/22/1985 |
| 4487835 | Plasmid having temperature dependent plasmid copy number Gene products of plasmid DNA, such as proteins, are prepared in high yields by cultivating bacteria carrying a plasmid which shows a controlled constant plasmid copy number at one temperature and a much higher or totally uncontrolled copy number at a diff... | 12/11/1984 |
| 4193985 | Multiple-units drug dose A controlled release multiple-units drug dose is described, which comprises a tablet or a capsule enclosing a plurality of subunits, each containing a therapeutically active agent and being enclosed in an insoluble membrane allowing for diffusion of the j... | 03/18/1980 |
| 3954959 | Oral drug preparations Oral drug preparations are described, having a protracted effect and a suitable rate of release of the drug during its period of action, said preparations comprising a pharmaceutically active component to which has been admixed one or more buffers, and po... | 05/04/1976 |
