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Assignee: AVL Medical Instruments AG


Location: Schaffhausen, CH
No. of patents: 69

1    
NumberTitleIssue Date
6254829Optochemical sensor
There is disclosed an optical sensor including a matrix containing a luminescence indicator whose luminescence may be quenched by oxygen. The optical sensor contains at least one agent capable of deactivating singlet oxygen and has an enhanced stability r...
07/03/2001
6238930Layer structure for determination of analyte concentration based on micellar recognition system
Starting from two non-miscible phases, i.e., a lipophilic and a hydrophilic phase, a surface-active substance and a recognition component, a micellar recognition system is built in a suitable manner and is incorporated into a layer structure. The micellar...
05/29/2001
6214185Sensor with PVC cover membrane
The invention is concerned with a sensor for the determination of the concentration and the detection of an enzyme substrate in a liquid sample, the sensor comprising an enzyme capable of reacting with the enzyme substrate while producing a substance dire...
04/10/2001
6211359Triaza-cryptand and method of determining an alkali ion
The invention relates to a triaza-cryptand of the general Formula I ##STR1## wherein a is selected from the group consisting of 0 and 1, b and c independently are selected from the group consisting of 0 and 1, with the proviso that not both of b and c are 0, d...
04/03/2001
6174728Control or calibration standard for use with instruments for optical measurement of hemoglobin concentration in blood samples
A control or calibration standard for use with instruments for the optical measurement of the hemoglobin content in blood samples, features scattering particles or beads dispersed in aqueous electrolyte solution. To prevent sedimentation of the beads duri...
01/16/2001
6171866Luminescence indicator for determining calcium ions
The invention relates to a compound having the general Formula I: ##STR1## including its salts, where Z is either the group having the general Formula II: ##STR2## where R1 is alkyl having 1-4 C atoms, alkoxyalkyl having 2-5 C atoms or ary...
01/09/2001
6124135Method of determining an alkali ion
The invention relates to a method of determining an alkali ion in a sample, wherein the alkali ion is contacted with a compound having a luminophoric moiety and an ionophoric moiety, which ionophoric moiety reacts with the alkali ion present in the sample...
09/26/2000
6103197Method and apparatus for optically determining total hemoglobin concentration
In a method of optically determining the total hemoglobin concentration (tHb) in non-hemolyzed whole blood, using at least two wavelengths for measuring, a first wavelength of λ805 nm is employed, such that the follo...
08/15/2000
6099510Device for withdrawing a liquid from a sealed glass ampoule
A device for withdrawing a liquid from a sealed glass ampoule includes a frame holding the sealed glass ampoule in upright or slightly inclined position, such that a tip of the ampoule points upwardly. An element is provided which will press or knock agai...
08/08/2000
6047719Method and device for production of high-precision, continuous streams of mixed gas
In a gas mixing system for producing high-precision, continuous streams of mixed gas consisting of a plurality of individually metered gas components, with an individual gas line including a pressure reducing element and, if desired, a precision pressure ...
04/11/2000
6046055Luminescence-optical method and sensor layer for quantitative determination of at least one chemical component of a gaseous or liquid sample
In a sensor layer for quantitative determination of at least one chemical component in a gaseous or liquid sample medium containing a chromophore which is directly or indirectly responsive to the component being determined by changing its absorption spect...
04/04/2000
6040190Method for determining the concentration C of an absorbent homogeneously distributed in a carrier
For the purpose of determining the concentration c of an absorbing medium distributed homogeneously in a carrier, even if the film thickness d of the carrier is unknown, an absorbing medium is used whose measured absorption a(λ) deviates from Lambert-Bee...
03/21/2000
6037178Method for quality control of an analyzing system
Quality control of an analyzing system that includes a portable analyzer with insertable single-use cartridges whose sample chamber contains optical and/or electrochemical sensors is accomplished by bringing the sensors in the single-use cartridge into co...
03/14/2000
6001228Device for performing measurements in fluids
A device for performing electrochemical and/or optical measurements in fluids, includes a sensor part of substantially planar configuration carrying a plurality of sensors that are connected to conductive paths; a cover part, which includes a groove-shape...
12/14/1999
6001999Luminescence indicator including ionophoric moiety
The invention relates to a compound having the general Formula I in which one of the groups R1,R2,R3,R4,R5,R6 and R7 represents an ionophoric moiety and the remaining groups each ...
12/14/1999
5981746Luminescence indicator
The invention relates to a compound having the general Formula I ##STR1## in which one of the groups R1, R2, R3, R4, R5, R6 and R7 represents an ionophoric moiety and the remaini...
11/09/1999
5952491Method of determining an alkali ion
The invention relates to a method of determining an alkali ion in a sample, wherein the alkali ion is contacted with a compound having a luminophoric moiety and an ionophoric moiety, which ionophoric moiety reacts with the alkali ion present in the sample...
09/14/1999
5948366Glass ampoule for holding a drug a calibration liquid or a quality control liquid
In a glass ampoule for holding a drug, a calibration liquid or a quality control liquid, whose bottom is flat or recessed towards the interior of the ampoule, the bottom area is shaped and/or coated such that a predefined breaking site is provided, which ...
09/07/1999
5942189Luminescence-optical method and sensor layer for quantitative determination of at least one chemical component of a gaseous or liquid sample
In a sensor layer for quantitative determination of at least one chemical component in a gaseous or liquid sample medium containing a chromophore which is directly or indirectly responsive to the component being determined by changing its absorption spect...
08/24/1999
5928957Determination of analyte concentration based on a micellar recognition system and structured layers therefor
Starting from two non-miscible phases, i.e., a lipophilic and a hydrophilic phase, a surface-active substance and a recognition component, a micellar recognition system is built in a suitable manner and is incorporated into a layer structure. The micellar...
07/27/1999
5928918Preparation of a hydrophobic polymer matrix containing immobilized enzymes
Biological components such as enzymes are immobilized in a three-dimensional cross-linked hydrophobic polymer. An enzyme is mixed with an aqueous solvent and a non-crosslinked prepolymer having an essentially nonpolar main chain with attached polar hydrop...
07/27/1999
5898487Apparatus and method for determining the concentrations of hemoglobin derivatives
An apparatus for determining the concentrations of n hemoglobin derivatives in a sample of undiluted, unhemolyzed whole blood provided in a cuvette, employs a device producing a primary light beam formed of at least n substantially monochromatic, narrow-b...
04/27/1999
5866433Optochemical fluorescence sensor and method for measuring the concentration of at least one analyte in a sample
An optochemical fluorescence sensor with a biorecognitive layer for measuring the concentration of one or more analytes in a sample is provided with at least one island layer which is applied on a sensor substrate. The islands of the island layer are in t...
02/02/1999
5779978Measuring assembly for luminescence analysis
A measuring assembly comprises a supporting element transparent to excitation and measurement radiation, which is provided with a number of preferably different luminescence-optical sensor elements on a first boundary face. Via a second boundary face exci...
07/14/1998
5773301Method for optically determining total hemoglobin concentration
In a method of optically determining the total hemoglobin concentration (tHb) in non-hemolyzed whole blood, using at least two wavelengths for measuring, a first wavelength of λ805 nm is employed, such the following ...
06/30/1998
5723340Optical indicator for determining the activity of an ion in a sample
An optical indicator for determining the activity of an ion in a sample is provided with an ionophor which is capable of selectively binding the ion to be measured. The ionophor has at least two functional groups that can form an electron donor acceptor (...
03/03/1998
5683658Reagent bottle
A reagent bottle suitable for insertion into a sample analyzer features a sample discharge opening plugged by an elastic, pierceable stopper, and an air inlet. Both the sample discharge opening and the air inlet are located on the same side of the reagent...
11/04/1997
5683562Planar sensor for determining a chemical parameter of a sample
A planar sensor for determining a chemical parameter of a sample, includes a substrate whose surface is at least partly plane and is provided with at least one potentiometric or amperometric and, possibly, an optical transducer, and one or more biochemica...
11/04/1997
5658451Method for calibration of a pH measuring element
In a method for calibration of a pH measuring element whose ion-permeable, hydrophilic polymer layer is brought into contact with an aqueous solution prior to calibration, the aqueous solution is displaced or replaced by a gaseous calibrating medium, and ...
08/19/1997
5628353Method and device for withdrawing a liquid from a sealed glass ampoule
For the purpose of automatically drawing a liquid from a sealed glass ampoule the latter is held in a support in upright position with the ampoule bottom facing upwards, and the bottom is destroyed mechanically by inserting a withdrawing element. The liqu...
05/13/1997
5627504Electromagnetic actuating device, in particular for a valve
Electromagnetic actuating device, in particular for a valve, includes a plunger which is axially movable between two extreme positions, an electromagnetic coil surrounding the plunger actuating it, and a permanent magnet holding the plunger in one of its ...
05/06/1997
5611998Optochemical sensor and method for production
An optochemical sensor for measuring concentrations of analytes is provided with a reactive matrix preferably made of polymeric material capable of swelling. Further provided are a mirror layer and a layer of a plurality of discrete islands that are elect...
03/18/1997
5551437Sensor for measuring blood pressure
A sensor with a first, second and third force pick-up includes a piece of foil made of piezoelectric material which serves all three pick-ups and carries a number of electrodes. The second and third pick-up are located one on either side of the first pick...
09/03/1996
5527706Method for mixing two initial solutions
In a process for mixing two initial solutions to produce a working solution with an accurately defined mixing ratio, the two initial solutions are coarsely mixed in a first step, having a mixing ratio lying within a given range, and the value of an intern...
06/18/1996
5513859Sealing element
A fluid-tight connection of capillary channels in components which are detachable from each other is established with the use of a sealing element. In order to compensate for slight deviations between the channel axes during the coupling of the components...
05/07/1996
5507936Member for the formation of at least one electrode and/or one sensor
A member has a solid carrier and a thin oxide layer which is arranged thereon and consists of iridium oxide and/or possibly at least one oxide of at least one other metal belonging to the fifth or sixth period and to one of the subgroups 5b, 6b, 7b and 8 ...
04/16/1996
5496521Analyzing device including an ion-permeable channel connecting a sample chamber with a reaction space
In a device for determining the concentration of a reagent from a group consisting of gases with acid or alkaline reaction in aqueous environments, and volatile acids and bases in liquid or gaseous samples, a sample chamber is situated in a housing and a ...
03/05/1996
5489515Device for analyzing the metabolism of cells
A device for analyzing the metabolism of cells includes a supporting base which carries a pH measuring electrode, a control electrode designed for proton exchange with the liquid, a reference electrode, and a counterelectrode, and which, together with at ...
02/06/1996
5474276Valve for control of a branch line
In order to avoid dead volumes in a valve for control of a branch line departing from the main line in a valve chamber located in a valve housing, the valve chamber contains an elastomer part provided with a main channel and a branch channel departing fro...
12/12/1995
5464587Luminescence-optical indicator for determining the activity of alkali metal ions in a sample solution
A luminescence-optical indicator for determining the activity of alkali metals based on decay time includes at least three components that are chemically bound to one another, i.e., a fluorophor, a functional group with which the luminescence decay time o...
11/07/1995
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