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| Number | Title | Issue Date |
| 8138204 | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders The subject invention provides stereoisomeric compounds of formula (X): wherein the variables are as defined herein, and compositions for the safe and effective treatment of various gastrointestinal... | 03/20/2012 |
| 8093237 | Dibenzo[b,f][1,4]oxazapine compounds The present invention relates to 11-(piperazin-1-yl)dibenzo[b,f][1,4 ]oxazapine compounds of the formula: where the variables are as defined herein, their salts and pharmaceutically acceptable compositions thereof. Methods of... | 01/10/2012 |
| RE42412 | Materials and methods for the treatment of gastroesophageal reflux disease The subject invention provides novel compounds and compositions for the safe and effective treatment of gastroesophageal reflux and related conditions. In a preferred embodiment, the compositions of the subject invention comprise esterified cisapride derivatives. Th... | 05/31/2011 |
| RE41289 | Ultrashort acting hypnotic barbiturates The subject invention concerns novel compounds that are useful as ultrashort acting hypnotic barbiturates. Specifically exemplified are derivatives of barbituric and thiobarbituric acids. They are rapidly metabolized by blood and tissue enzymes to form polar metabol... | 04/27/2010 |
| 7666902 | Haloalkyl ester derivatives of coumarin for the treatment of coagulation disorders The subject invention provides anticoagulant compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R1, R3, n and Ar are as defined herein. The compounds of the subject inventio... | 02/23/2010 |
| 7629466 | Synthetic methods and intermediates for steroisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders The subject invention provides methods and/or processes for making stereoisomeric compounds of formula (X): wherein the variables are as defined herein, and compositions for the safe and effective t... | 12/08/2009 |
| 7501436 | 5-HT3 receptor antagonists and methods of use The subject invention provides useful and novel 5-HT3 antagonists. The subject invention also provides methods for synthesizing the compounds of invention. The invention also provides methods for the treatment of irritable bowel syndrome and other such conditions. | 03/10/2009 |
| 7384973 | Materials and methods for treating hypercholesterolemia The subject invention provides novel HMG-CoA-reductase inhibitors. In a preferred embodiment, the HMG-CoA reductase inhibitors of the subject invention can be deactivated to a primary inactive metabolite by hydrolytic enzymes. Compounds of the present invention can ... | 06/10/2008 |
| 7351842 | Compounds for treatment of cardiac arrhythmia and methods of use The subject invention provides novel compounds for treatment of cardiac arrhythmia and methods of use. ... | 04/01/2008 |
| 7326787 | Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders The subject invention provides methods and/or processes for making stereoisomeric compounds of formula (X): wherein the variables are as defined herein, and compositions for the safe and ... | 02/05/2008 |
| 7176218 | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders The subject invention provides stereoisomeric compounds of formula (X): wherein the variables are as defined herein, and compositions for the safe and effective treatment of various gastr... | 02/13/2007 |
| 7105568 | Compounds for treatment of cardiac arrhythmia and methods of use The subject invention provides novel compounds for treatment of cardiac arrhythmia and methods of use. ... | 09/12/2006 |
| 7041673 | Ultrashort acting hypnotic barbiturates The subject invention concerns novel compounds that are useful as ultrashort acting hypnotic barbiturates. Specifically exemplified are derivatives of barbituric and thiobarbituric acids. They are rapidly metabolized by blood and tissue enzymes to form polar metabol... | 05/09/2006 |
| 7022722 | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis The subject invention provides pharmaceutical compounds useful in the treatment of Type II diabetes. These compounds are advantageous because they are readily metabolized by the metabolic drug detoxification systems. Particularly, thiazolidinedione analogs that have... | 04/04/2006 |
| 7001915 | Ultrashort-acting opioids for transdermal applications The subject invention encompasses compounds of the formula: wherein R1, R2, and R3 are as defined herein. The subject invention also concerns methods for synthesizing the compounds of th... | 02/21/2006 |
| 6951877 | Materials and methods for treating hypercholesterolemia The subject invention provides novel HMG-CoA-reductase inhibitors. In a preferred embodiment, the HMG-CoA reductase inhibitors of the subject invention can be deactivated to a primary inactive metabolite by hydrolytic enzymes. Compounds of the present invention can ... | 10/04/2005 |
