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Assignee: ALS Therapy Development Foundation, Inc.


Location: Cambridge, MA
No. of patents: 4

NumberTitleIssue Date
7902185Treatment of neurodegenerative diseases using proteasome modulators
Methods for modulating proteasome activity in a subject is provided. Proteasome activity is modulated by administering a therapeutically effective amount of proteasome modulating pharmacological agent to a subject. In a preferred embodiment, the proteasome modulatin...
03/08/2011
7273888Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis
The present invention provides methods and compositions for modulating polyamine pathway activity as a means for ameliorating neurodegenarative disorders. In particular, for ameliorating the symptoms or onset of amyotrophic lateral sclerosis (ALS) by modulating the ...
09/25/2007
7211602Treatment of neurodegenerative disorders through the modulation of the polyamine pathway
The present invention provides methods and compositions for modulating polyamine pathway activity as a means for ameliorating neurodegenarative disorders. In particular, for ameliorating the symptoms or onset of amyotrophic lateral sclerosis (ALS) by modulating the ...
05/01/2007
7030126Use of polyamine analogs for amyotrophic lateral sclerosis
The present invention provides methods and compositions for modulating polyamine pathway activity as a means for ameliorating neurodegenarative disorders. In particular, for ameliorating the symptoms or onset of amyotrophic lateral sclerosis (ALS) by modulating the ...
04/18/2006
 
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