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| Number | Title | Issue Date |
| 6361956 | Biospecific, two photon excitation, fluorescence detection and device A method for measuring the end point and for monitoring the real time kinetics of a bioaffinity reaction in biological fluids and suspensions, employing microparticles as bioaffinity binding solid phase, biospecific reagent labelled with a fluorescent lab... | 03/26/2002 |
| 6342397 | Homogeneous biospecific assay using a solid phase, two-photon excitation and confocal fluorescence detection A homogeneous biospecific assay method for an analyte in solution or in a biological suspension, in which a biospecific reagent competitively binding an analyte and a ligand labeled with a fluorescent molecule, is reacted with and bound to a solid phase, ... | 01/29/2002 |
| 6310354 | Method and a device for monitoring nucleic acid amplification reactions A method for quantitatively measuring nucleic acid amplification reactions, especially the polymerase chain reaction, employing microparticles as hybridization solid phase, a probe sequence labeled with a fluorescent label and a fluorescence detection sys... | 10/30/2001 |
| 6204068 | Biospecific assay method This invention is thus related to a biospecific multiparameter assay employing single molecule detection. In particular, this invention is related to a new method for determination of several different biomolecules simultaneously in the same reaction solu... | 03/20/2001 |
| 6177277 | Flow fluorometric method This invention is related to a flow fluorometric device and method employing a two-photon excitation and/or confocal optical set-up. The optical set-up of this invention is optimal for counting small fluorescent biological particles. The active focal volu... | 01/23/2001 |
| 5891738 | Biospecific multiparameter assay method The object of this invention is an improved method for biospecific multiparameter assay method based on the use of different categories of microparticles as solid support for different bioaffinity reagents. This invention allows the use of microparticles ... | 04/06/1999 |