Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
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| Application No. | Application Title | Issue Date |
| 20120125843 | METHODS AND MATERIALS FOR PERFORMING HYDROPHOBIC INTERACTION CHROMATOGRAPHY A method for performing hydrophobic interaction chromatography includes providing at least one wall defining a chamber having an inlet and an exit, and a stationary phase disposed within the chamber. The stationary phase comprises particles or monolith having a hydropho... | 05/24/2012 |
| 20120103075 | Automated Dilution For Liquid Chromatography Described are a method and system for diluting a sample in a liquid chromatography system. A sample flowing at a first flow rate is combined for a predetermined time with a diluent flowing at a second flow rate to generate a volume of diluted sample. The diluted sample ... | 05/03/2012 |
| 20120052522 | Apparatus And Method For The Study Of Metabolism Embodiments of the present invention feature methods and apparatus in which fluids circulating between a plurality of vessels containing different cell types or tissues are monitored for metabolites following the introduction of a sample.... | 03/01/2012 |
| 20120048002 | Devices, Kits And Methods For Performing Chemical Processing Embodiment of the present invention features a device, method and kit for performing one or more processing steps on a sample. The device includes a housing and a processing component. The housing has a first vessel connector for receiving a first vessel and a second ve... | 03/01/2012 |
| 20120040968 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND Provided is a compound useful as an inhibitor against the kinase activity of EML4-ALK fusion protein. As a result of intensive and extensive studies on compounds having inhibitory activity against the kinase activity of EML4-ALK fusion prot... | 02/16/2012 |
| 20120037724 | Electrospray Interface To A Microfluidic Substrate An apparatus for chemical separations includes a microfluidic substrate having an outlet aperture for outputting an eluent of a sample, a spray unit having an inlet to receive the eluent and an outlet to emit a spray of the eluent, and a force-applying unit. The spray u... | 02/16/2012 |
| 20120032628 | Intake Profile For Optimized Utilization Of Motor Characteristics Systems and methods for operating a stepper motor of a pump at a desired low velocity include memory for storing information corresponding to an intake velocity profile. The intake velocity profile represents an optimized acceleration curve for operating the stepper mot... | 02/09/2012 |
| 20120024399 | Electrospray Interface To A Microfluidic Substrate A liquid-chromatography module includes a microfluidic cartridge housing a microfluidic substrate with a channel for transporting fluid. The microfluidic substrate has fluidic apertures through which fluid is supplied to the channel. One side of the cartridge has nozzle... | 02/02/2012 |
| 20110278214 | Liquid-Chromatography Conduit Assemblies Having High-Pressure Seals A method for making a liquid-chromatography apparatus includes inserting two inner conduits into an intermediate tube, inserting the intermediate tube into an outer tube, forming a proximal seal between the intermediate tube and at least one of the inner conduits, and f... | 11/17/2011 |
| 20110272855 | Techniques For Patterning Valve Components Described are techniques for fabricating one or more parts of a valve used in a liquid chromatography system. At least one of a rotor and a stator are provided. The rotor is included in the valve and has a first surface facing a stator. The stator is included in the val... | 11/10/2011 |
| 20110271755 | Apparatus And Methods For The Measurement Of Mass Related Parameters Embodiments of the present invention are directed to resonating detection devices in which the sample flows through a conduit having a section in which the conduit is grouped or concentrated with the point of maximum movement.... | 11/10/2011 |
| 20110269241 | Methods And Kits For The Determining The Presence Or Absence Of Cyanobacteria Toxins Embodiments of the present invention are directed to kits and methods for the detection of toxins produced by cyanobacteria. The methods and kits feature sample preparation steps with weak cationic and anionic exchange resins and small particle analytical columns operat... | 11/03/2011 |
| 20110266434 | Stacked-Electrode Peptide-Fragmentation Device A chemical processing apparatus includes a fragmentation device that includes a linear set of stacked electrodes and a voltage control module that forms DC potential wells of opposite polarity for mutual confinement of opposite polarity ions. A method of protein analysi... | 11/03/2011 |
| 20110266433 | Apparatus And Methods For Gas Chromatography - Mass Spectrometry The invention provides improved apparatus for, and methods of, ionizing analyte molecules in a flow of gas, typically at or around atmospheric pressure. The invention may be used to facilitate mass spectrometric analysis of analytes comprised in the effluent form a gas ... | 11/03/2011 |
| 20110263033 | Apparatus And Methods For Performing Photoreactions And Analytical Methods And Devices To Detect Photo-Reacting Compounds Embodiments of the present invention are directed to devices and methods for performing photoreactions of photo-reacting compounds in solution. The invention features a vessel and a light source. The vessel has at least one wall defining a chamber. The chamber, for perf... | 10/27/2011 |
| 20110263029 | Methods And Kits For The Determining The Presence Or Absence Of Ergot Alkaloids The present invention is directed to methods and kits for the determining the presence or absence of ergot alkaloids in sample which use chromatographic instrumentation and columns operating at a pressure of 4,000 to 15,000 psi and columns with 1-3 micron particle size ... | 10/27/2011 |
| 20110261642 | Valve Switch Modulation For Reducing Errors Due Oscillations Of The Inlet Fluid Of A Pump System Described is a method of reducing liquid composition errors in a low-pressure mixing pump system. Packets representing the switching intervals of each component of the desired fluid mixture are provided to an intake of the mixing pump system. For each packet, a switchin... | 10/27/2011 |
| 20110260049 | Method And Apparatus For Identifying Proteins In Mixtures Protein identification in a complex sample begins by selecting a database having proteins likely to be in the sample. In-silico digestion is performed and a target peptide is selected from produced peptides. The masses of the Y- and B-ion fragments of the target peptide... | 10/27/2011 |
| 20110259827 | Device, Apparatus And Method For Performing Separations Embodiment of the present invention feature a device having a body, a separation media and a frit element. The exterior surface of the body has a first attachment means positioned radially about at least one of the media chamber and the frit section to form a compact as... | 10/27/2011 |
| 20110259089 | Devices Having An Inert Surface And Methods Of Making Same The present invention features devices and methods of making such devices for performing liquid chromatography having at least one wetted surface having a composition of a polysilazane.... | 10/27/2011 |
| 20110315633 | Rotating Valve Described is a rotary valve including a stator element and a rotor element. The stator element defines a first inlet passage, a second inlet passage, and a first outlet passage, respectively, having a first inlet port, second inlet port and first outlet port in a stator... | 12/29/2011 |
| 20110290994 | Methods And Apparatus For Performing Gas And Liquid Mass Spectrometry Embodiments of the present invention feature devices and methods for performing gas chromatography and liquid chromatography with mass spectrometry. The device and method feature a removable housing which housing contains the gas samples when the mass spectrometry recei... | 12/01/2011 |
| 20110247403 | Apparatus And Methods For Multidimensional Analysis The invention provides improved methods and apparatus for multidimensional analysis, especially for multidimensional liquid chromatography. Methods and apparatus for the quantitative determination of one or more components comprised in a sample mixture are described. Me... | 10/13/2011 |
| 20110226941 | Techniques For Performing Retention-Time Matching Of Precursor And Product Ions And For Constructing Precursor And Product Ion Spectra Techniques are described for matching a precursor ion with one or more related product ions, including providing a plurality of input data sets obtained from a plurality of injections, each of the plurality of input data sets including a same precursor ion and one or mo... | 09/22/2011 |
| 20110202188 | DEVICES, SYSTEMS AND METHODS FOR FLOW-COMPENSATING PUMP-INJECTOR SYNCHRONIZATION Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream, to enhance chromatographic performance related to retention time and reproducibility. The preferred e... | 08/18/2011 |
| 20110198842 | Device And Method For Connecting Fluid Conduits A connector for connecting a first conduit to a second conduit including a body having a passageway therethrough, a first cavity and a second cavity, a first sealing member, a second sealing member, a first compression, a second compression fitting, a first set of one o... | 08/18/2011 |
| 20110197655 | MULTI-LAYERED CERAMIC MICRO-GAS CHROMATOGRAPH AND METHOD FOR MAKING THE SAME A micro-gas chromatograph column is formed by texturing a channel into a plurality of green-sheet layers, which are then sintered together to form a substantially monolithic structure. A thick-film paste may be added to the channel textured in the green-sheet layers to ... | 08/18/2011 |
| 20110195513 | Methods And Kits For The Determination Of The Presence And Quantity of Vitamin D Analogs In Samples Embodiments of the present invention are directed to methods and kits for determining the presence or absence, and the amount if present, of vitamin D analogs in samples. One embodiment of the present method for detecting the presence or absence of vitamin D analogs in ... | 08/11/2011 |
| 20110141465 | Light-Guiding Flow Cells And Analytical Devices Using The Same A flow cell for a photometric device includes a module having a body with a distal face defining an annular channel. The body also defines an axial central passage and an axial flow channel. A second module has a body with a proximal face defining an annular channel. Th... | 06/16/2011 |
| 20110134428 | Evaporative Light Scattering Detector Described is a detector for receiving the eluent from a liquid- or supercritical-fluid chromatograph in which a signal indicative of the presence of an analyte in the eluent is generated by the scattering of light by desolvated particles of the analyte. The detector inc... | 06/09/2011 |
| 20110121093 | Apparatus And Methods For Making Analyte Particles A device for making particulate analyte molecules comprising a nebulizer producing a plume of liquid droplets, a vessel having a chamber to receive the plume in which the chamber has a nebulization section, a desolvation section. The nebulization section is cooled to fo... | 05/26/2011 |
| 20110107822 | Interfacing With A Digital Microfluidic Device Described are techniques for use in connection with analyzing a droplet. One or more droplets of a sample are formed on a surface of a digital microfluidic device. The droplets are manipulated to perform processing using said one or more droplets generating one or more ... | 05/12/2011 |
| 20110100114 | Thermal Loop Flow Sensor A flow sensor includes a fluidic component, such as a tube, a heat source, an upstream temperature sensor, and a downstream temperature sensors. The fluidic component defines a flow path having inlet and outlet ends disposed closer to each other than to a mid-point of t... | 05/05/2011 |
| 20110049056 | COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY Novel porous materials comprising nanoparticles, use in chromatographic separations, processes for its preparation, and separations devices containing the chromatographic material are described by the instant invention. In particular, the disclosure describes porous ino... | 03/03/2011 |
| 20110044587 | Methods Of making And Using And Apparatus And Devices For Placing Light And Sample In Photo-Emitting Or Absorbing DeviceM The present invention relates to a device having an optical fiber coupled to a high pressure containment vessel and a method for making the same. The high pressure containment vessel can be an optical fiber based flow cell for a chromatography system.... | 02/24/2011 |
| 20110020939 | Chromatography-Based Monitoring and Control of Multiple Process Streams An analytical apparatus includes a sample-injection valve, a sample pump, at least two sources of standards, and a selection valve. The sample-injection valve has an output port in fluid communication with a LC column, and an input port in fluid communication with a mob... | 01/27/2011 |
| 20110016955 | Sample Dilution for Chromatography of Multiple Process Streams A method of liquid chromatography includes providing an injection valve, drawing a sample and a diluent while mixing, pushing the mixed sample and diluent onto a sample loop of the injection valve, and injecting the mixed sample and diluent. An analytical apparatus incl... | 01/27/2011 |
| 20100324159 | NOVEL ION EXCHANGE POROUS RESINS FOR SOLID PHASE EXTRACTION AND CHROMATOGRAPHY Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting ... | 12/23/2010 |
| 20100322281 | Large Array Defferential Scanning Calorimeter, DSC Measuring Unit Embodiments of the present invention feature a method and apparatus for an energetics-based approach to screen and to characterize binding interactions between potential therapeutic (or diagnostic) agents and unknown target molecules. The methods and apparatus detect th... | 12/23/2010 |
| 20100320374 | DEVICES AND METHODS FOR PERFORMING MASS ANALYSIS Embodiments of the present invention feature devices and methods for performing mass analysis. One embodiment of the device comprises an inlet housing for mounting on the first wall between the area of low pressure and the area of high pressure. The inlet housing has pa... | 12/23/2010 |
