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| Application No. | Application Title | Issue Date |
| 20120107952 | MICROWAVE-ACCELERATED PLASMONICS The present invention relates to systems and methods using microwave accelerated surface plasmonics for the detection of target species, wherein the system has a metallic surface and the system is exposed to microwave energy for increasing detection time and/or the reac... | 05/03/2012 |
| 20110166206 | UBIQUILIN REGULATION OF PRESENILIN ENDOPROTEOLYSIS, AND SUPPRESSION OF POLYGLUTAMINE-INDUCED TOXICITY IN CELLS Use of ubiquilin is described, including utilization for reducing fragmentation of presenilin 1 and 2 and to modulate γ-secretase components, Pen-2 and Nicastrin, as well as utilization for inducing increased levels of ubiquilin to reduce aggregation of polyglutamine e... | 07/07/2011 |
| 20100221241 | CONSTRAINED HIV ENVELOPE-BASED IMMUNOGEN THAT SIMULTANEOUSLY PRESENTS RECEPTOR AND CORECEPTOR BINDING SITES The present invention relates to a soluble binding complex comprising a soluble gp120 trimer, in which only two gp120 protomers have CD4 binding sites occupied by interconnecting CD4 mimetic moieties, thereby allowing for the exposure of CD4-induced epitopes on the mime... | 09/02/2010 |
| 20100099747 | REDUCTION OF POLYALANINE-INDUCED PROTEIN AGGREGATES AND TOXICITY BY UBIQUILIN A method for decreasing cell death in a cell exhibiting aggregation of polyalanine-containing proteins. The method includes introduction of an expression vector to a host cell comprising a nucleotide sequence encoding ubiquilin, followed by maintaining the transformed h... | 04/22/2010 |
| 20100093562 | METAL COATED VIRUS-BASED NANOELECTRODES AND METHOD OF ASSEMBLING OF SAME The present invention relates to high content surface areas containing nickel and/or cobalt metallic compounds assembled on a modified Tobacco mosaic virus (TMV) template, wherein the modified TMV template is engineered to encode unique placement of cysteine residues th... | 04/15/2010 |
| 20100093062 | TRANSFECTION SYSTEM FOR PERKINSUS SPECIES A Perkinsus heterologous expression system that is useful to produce recombinant proteins, e.g., from related parasites of medical and veterinary relevance. This expression system increases the number of genes that can be targeted for protein structure/function s... | 04/15/2010 |
| 20100062545 | BIOASSAYS USING PLASMONIC SCATTERING FROM NOBLE METAL NANOSTRUCTURES The present invention relates to detecting and/or measuring scattering effects due to the aggregating metallic nanostructures or the interaction of plasmonic emissions from approaching metallic nanoparticles. The scattering effects may be measured at different angles, d... | 03/11/2010 |
| 20100035960 | BIOSYNTHETIC PATHWAY AND GENES REQUIRED FOR TROPODITHIETIC ACID BIOSYNTHESIS IN SILICIBACTER TM1040 Production and use of a sulfur-containing compound, tropodithietic acid (TDA), from the roseobacter Silicibacter sp. TM1040 is described. Specifically, a biosynthetic and regulatory pathway for TDA biosynthesis in roseobacters is described. The TDA produce... | 02/11/2010 |
| 20100028983 | MICROWAVE ACCELERATED ASSAYS The present invention provides for increasing fluorescence detection in surface assay systems while increasing kinetics of a bioreaction therein by providing low-power microwaves to irradiate metallic materials within the system in an amount sufficient to increase heat ... | 02/04/2010 |
| 20100003695 | MICROWAVE TRIGGER METAL-ENHANCED CHEMILUMINESCENCE (MT MEC) AND SPATIAL AND TEMPORAL CONTROL OF SAME The present invention relates to a method of imaging structures and features using plasmonic emissions from metallic surfaces caused by chemiluminescence based chemical and biological reactions wherein imaging of the reactions is enhanced by the use of microwave energy ... | 01/07/2010 |
| 20090325199 | NANOSTRUCTURES FOR POLARIZED IMAGING AND RECEPTOR/LIGAN QUANTIZATION: BREAKING THE DIFFRACTION LIMIT FOR IMAGING The present invention relates to affinity biosensing using polarization of light scattering of aggregated noble metallic nanostructures to determine concentration of an analyte in a test sample. This new sensing system utilizes the changes in polarized plasmonic scatter... | 12/31/2009 |
| 20090215066 | METHOD AND ASSAY FOR EARLY DIAGNOSIS OF PROSTATE CANCER A method and assay are described for determining prostate cancer and the general stage of progression of such cancer by quantifying levels of promoter methylation of gal-3, optionally in combination with the quantification of the level of GSTP1 promoter methylation, whe... | 08/27/2009 |
| 20090142847 | METAL ENHANCED FLUORESCENCE-BASED SENSING METHODS The present invention relates to metallic-surface detection systems for determining target substances including free bilirubin in neonatal serum in the presence of a predominantly high background of bilirubin bound Human Serum Albumin (HSA) or sensing and isolating targ... | 06/04/2009 |
| 20090142429 | SILICIBACTER SP. STRAIN USEFUL FOR GENETIC TRANSFORMATION OF MARINE ALGAE AND PRODUCTION OF ANTIBIOTIC AGENTS A Silicibacter sp. strain useful for genetic transformation of marine algae and production of antibiotic agents is described. Silicibacter sp. TM1040 is a genetically tractable member of the marine Roseobacter clade of bacteria that forms an intimat... | 06/04/2009 |
| 20090004461 | Metal-Enhanced Fluorescence from Plastic Substrates The present invention relates to methods for functionally modifying a polymeric surface for subsequent deposition of metallic particles and/or films, wherein the polymeric surface is modified by increasing hydroxyl and/or amine functional groups thereby providing an act... | 01/01/2009 |
| 20080318281 | Thermostabillization of Dna Polymerase by Protein Folding Pathway from a Hyperthermophile Archaeon, Pyrococcus Furiosus The present invention relates to maintaining the activity and stability of enzymes and biologically active proteins at increased temperatures by contacting same with a combination of isolated passive and active chaperones from a hyperthermopilic Archaeon, wherein the ch... | 12/25/2008 |
