U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Icon_funbox Bizarre Patents

Patent No. 5500234

Crispy Chip Sandwich and Process of Producing a Sandwich Product

A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.

Newsletter  PatentStorm News

Make the Most of Our Site

See this month's Top Inventors and Most Cited Patents.

Stay on top of the latest innovations by subscribing to an RSS feed.

Registered users: Manage your profile.

 

Assignee: Novartis AG


Location: Basel, CH
No. of applications: 591

1                      
Application No.Application TitleIssue Date
20130123337RNAi Inhibition of Serum Amyloid A For Treatment of Glaucoma
RNA interference is provided for inhibition of serum amyloid A mRNA expression in glaucomas involving SAA expression....
05/16/2013
20130123290Pyrimidylaminobenzamide Derivatives for Treatment of Neurofibromatosis
The present invention relates to the use of pyrimidylaminobenzamide derivatives for the preparation of a drug for the treatment of non-cancerous, benign brain tumors, especially for the curative and/or prophylactic treatment of NF, and to a method of treating non-cancer...
05/16/2013
20130123272ORGANIC COMPOUND FOR USE IN THE TREATMENT OF LIVER CANCER
The use of 4-amino-5-fluoro-3[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one or a pharmaceutically acceptable salt or a tautomer thereof, or a hydrate or a solvate for the manufacture of pharmaceutical compositions for use in the treatment of hepatoc...
05/16/2013
201301232522,3,5-Trisubstituted Thiophene Compounds and Uses Thereof
The present invention provides a compound of formula I:

a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacolog...

05/16/2013
20130122543IMPROVED CELL CULTURE MEDIUM
The present application describes an optimized medium for growth of mammalian cells as well as polypeptide production. The cell culture medium is characterized by a Sow ratio of sodium to potassium ions, it further relates to the method of producing polypeptides using s...
05/16/2013
20130122487DECREASING POTENTIAL IATROGENIC RISKS ASSOCIATED WITH INFLUENZA VACCINES
Influenza viruses for use in preparing human vaccines have traditionally been grown on embryonated hen eggs, although more modern techniques grow the virus in mammalian cell culture e.g. on Vero, MDCK or PER.C6 cell lines. The inventor has realised that the conditions u...
05/16/2013
20130122171Dietary Fiber Composition
The present invention provides a chewable composition containing granules of water-soluble dietary fiber. The chewable composition has highly agreeable organolpetic properties and is consumable without the need of an ingestion aid....
05/16/2013
20130122064Ophthalmic Depot Formulations for Periocular or Suconjunctival Administration
The present invention relates to ophthalmic depot formulations comprising an active agent, e.g. embedded in a pharmacologically acceptable biocompatible polymer or a lipid encapsulating agent, e.g. for periocular or subconjunctival administration....
05/16/2013
20130122040FERMENTATION MEDIA FREE OF ANIMAL-DERIVED COMPONENTS FOR PRODUCTION OF DIPHTHERIA TOXOIDS SUITABLE FOR HUMAN VACCINE USE
The present invention relates to a fermentation medium for cultivating Corynebacterium diphtheriae. The present invention also relates to the use of the fermentation medium in processes for obtaining diphtheria toxin from the Corynebacterium diphtheriae ba...
05/16/2013
20130122004METHODS AND COMPOSITIONS USING FGF23 VARIANT POLYPEPTIDES
The present disclosure is directed to methods, kits and compositions for preventing or treating age-related conditions or metabolic disorders. The fusion polypeptides of the disclosure include FGF23 or an active fragment thereof. In one embodiment, the fusion polypeptid...
05/16/2013
20130118127SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING
The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves autoclaving, in a sealed lens package, a silicone hydrogel contact lens having a base coa...
05/16/2013
20130116181Method of treating dyspnea associated with acute heart failure
The disclosure pertains to methods of reducing decompensation through acute intervention including in subjects afflicted with acute decompensated heart failure. Particularly, the disclosure provides methods for treating acute cardiac decompensation by administering a ph...
05/09/2013
20130116178PHARMACEUTICAL COMPOSITIONS COMPRISING POLYETHYLENE GLYCOL HAVING A MOLECULAR WEIGHT OF LESS THAN 600 DALTONS
A liquid pharmaceutical composition comprising a biodegradable polymer, polyethylene glycol having a molecular weight of less than 600 Daltons, a pharmaceutically active agent and less than 0.5% of an biologically acceptable organic solvent....
05/09/2013
20130115238MENINGOCOCCAL FHBP POLYPEPTIDES
fHBP is a protein in Neisseria meningitidis. Three families of fHBP are known. To increase the ability of a fHBP protein to elicit antibodies that are cross-reactive between the families, fHBP is selected or engineered to have a sequence which can elicit broad-sp...
05/09/2013
20130109730TREATMENT OF LIVER DISEASES IN WHICH IRON PLAYS A ROLE IN PATHOGENESIS
The invention relates to the use of 4-[3,5-Bis-(2-hydroxyphenyl)-[1,2,4]-triazol-1-yl]benzoic acid (hereinafter referred to as “Compound I”) for the manufacture of pharmaceutical compositions for the treatment of liver diseases in humans in which iron plays a role i...
05/02/2013
20130109729PHARMACEUTICAL COMPOSITION
Provided are compositions comprising aqueous solutions of valsartan suitable for oral administration, preferably in pediatric and geriatric populations. Methods for making such compositions and methods for their stabilization are provided....
05/02/2013
20130109682CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS
The present invention provides certain compounds of Formula (I):

and pharmaceutically acceptable salts thereof, as further described herein. Also provided are formulations comprising compounds of formula I, a...

05/02/2013
20130108675ORGANIC COMPOUNDS
A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol....
05/02/2013
20130108638ANTAGONIST ANTIBODIES AGAINST EPHB3
EphB3-specific antibodies are provided, along with pharmaceutical compositions containing such antibody, kits containing a pharmaceutical composition, and methods of preventing and treating an EphB3-related disease or disorder....
05/02/2013
20130106007PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION
The invention provide a new lens curing method for making hydrogel contact lenses. The new lens curing method is based on actinically-induced step-growth polymerization. The invention also provides hydrogel contact lenses prepared from the method of the invention and fl...
05/02/2013
20130106006METHOD FOR MOLDING AN OPHTHALMIC LENS AND DEVICE FOR APPLYING A COATING TO THE SURFACE OF AN OPHTHALMIC LENS MOLD
There are described a method for applying a coating to a surface of an ophthalmic lens mold. The mold includes male and female (20) mold halves, with each of the mold halves being provided with a lens forming surface (21). The method includes
    05/02/2013
20130102611IP RECEPTOR AGONIST HETEROCYCLIC COMPOUNDS
The present invention provides heterocyclic derivatives which activate the IP receptor. Activating the IP receptor signaling pathway is useful to treat many forms of PAH, pulmonary fibrosis and exert beneficial effects in fibrotic conditions of various organs in animal ...
04/25/2013
20130102594Pharmaceutical Formulation of Valsartan
The present invention relates to a pharmaceutical composition in a form of suspension for oral administration comprising valsartan or its pharmaceutically acceptable salts and at least one or two or more of the components selected from glycerol or syrup or the mixture t...
04/25/2013
20130102544Disease-Associated Proteins
Disclosed are methods and compositions for early diagnosis, monitoring and treatment of an ocular disorder. In particular, the invention relates to a novel protein, that is differentially transcribed and expressed in subjects suffering from retinal dystrophies and the l...
04/25/2013
20130102032CELL CULTURE MEDIUM
A cell culture medium with high content of choline chloride is provided. The cell culture media further comprise only moderate amounts of amino acids, in particular the amount of glutamine in the cell culture media is limited. The cell culture media can be used for larg...
04/25/2013
20130101629HOMOGENOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF
The present invention generally relates to homogeneous suspensions of small molecule immune potentiators (SMIPs) that are capable of stimulating or modulating an immune response in a subject in need thereof. The homogeneous suspensions may be used in combinations with v...
04/25/2013
20130101622IMIDAZOQUINOXALINE COMPOUNDS AS IMMUNOMODULATORS
The invention provides novel compositions comprising imidazoquinoxaline compounds of formula (I) and analogs thereof. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are nov...
04/25/2013
20130101609IRRADIATED BIODEGRADABLE POLYMER MICROPARTICLES
In one aspect, the present invention provides sterile microparticle compositions comprising biodegradable microparticles, which comprise at least one biodegradable polymer. In other aspects, the present invention provides methods of making and using such compositions as...
04/25/2013
20130097969PROCESS TO IMPROVE STABILITY OF A PHARMACEUTICAL COMPOSITION
The present invention describes in particular a method for stabilizing a pharmaceutical composition by contacting said composition with a polymeric material comprising in particular an ethylene oxide sterilization step....
04/25/2013
20130096337Process for Preparation of Optically Active Compounds using Transfer Hydrogenation
A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drug substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmetric catalytic reduction and trans...
04/18/2013
20130096168Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors
The present invention provides a compound of formula I;

or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1

04/18/2013
20130096149HETEROARYL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
The present invention provides compounds of Formula I:

    • wherein R1, R2
04/18/2013
20130096145Use of 1H-quinazoline-2,4-diones
The invention concerns the use of competitive AMPA receptor antagonists for the treatment, prevention or delay of progression of spasticity....
04/18/2013
20130096127SUBSTITUTED AMINOPROPIONIC DERIVATIVES AS NEPRILYSIN INHIBITORS
The present invention provides a compound of formula I′;

or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, B1, X and n are defined...

04/18/2013
20130096105ArylSulfonamide Based Matrix Metalloprotease Inhibitors
The present invention provides a compound of formula (I):

said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder...

04/18/2013
20130095235METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES
Described herein is a cost-effective and time-efficient method for making UV-absorbing contact lenses. In contrast to the conventional method for making UV-absorbing contact lenses which involves copolymerizing a lens forming composition including a UV-absorbing vinylic...
04/18/2013
20130095153STABLE METAL ION-LIPID POWDERED PHARMACEUTICAL COMPOSITIONS FOR DRUG DELIVERY
A microparticle for drug delivery comprises an active agent and an excipient, the excipient comprising a metal ion-lipid complex. The metal ion is chosen from the group consisting of lanthanide metals, actinide metals, group IIa and IIIb metals, transition metals or mix...
04/18/2013
20130090344Pharmaceutical compositions comprising 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-y1)-1H-benzimidazol-2-y1]-1H-quinolin-2-one lactate monohydrate
A pharmaceutical composition for oral administration comprising 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one monolactate monohydrate, a filler in an amount of 15 to 70% by weight, a disintegrant in an amount of less than 15% by ...
04/11/2013
20130090342BIPHENYL SUBSTITUTED 1,3-DIHYDRO-BENZOIMIDAZOL-2-YLIDENEAMINE DERIVATIVES
The invention relates to new derivatives of formula (I),

wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions compris...

04/11/2013
20130085161PIPERIDINYL SUBSTITUTED 1,3-DIHYDRO-BENZOIMIDAZOL-2-YLIDENEAMINE DERIVATIVES
The invention relates to new derivatives of formula (I),

wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions compris...

04/04/2013
1                      
 
Sign InRegister
Username  
Password   
forgot password?