Ballistic resistant body covering
A ballistic resistant body covering for protecting the torso, groin and neck area from ballistic missiles.
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| Application No. | Application Title | Issue Date |
| 20120129915 | ORGANIC COMPOSITIONS TO TREAT HSF1-RELATED DISEASES The present disclosure relates to methods of treating heat shock factor 1 (HSF1)-related diseases such as cancer and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF.... | 05/24/2012 |
| 20120129914 | ORGANIC COMPOSITIONS TO TREAT HSF1-RELATED DISEASES The present disclosure relates to methods of treating heat shock factor 1 (HSF1)-related diseases such as cancer and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF.... | 05/24/2012 |
| 20120129913 | dsRNA For Treating Viral Infection The invention relates to double-stranded ribonucleic acids (dsRNAs) targeting gene expression of phosphatidylinositol 4-kinase (PI4K), in particular human phosphatidylinositol 4-kinase, catalytic, beta polypeptide (PIK4CB) or human phosphatidylinositol 4-kinase, catalyt... | 05/24/2012 |
| 20120129871 | Crystalline form of an inhibitor of MDM2/4 and p53 interaction A crystalline form of (S)-1-(4-Chloro-phenyl)-7-isopropoxy-6-methoxy-2-(4-{methyl-[4-(4-methyl-3-oxo-piperazin-1-yl)-trans-cyclohexylmethyl]-amino}-phenyl)-1,4-dihydro-2H-isoquinolin-3-one, which is useful in the treatment of a disease or disorder associated with the in... | 05/24/2012 |
| 20120129766 | METHODS OF TREATING FGF21-ASSOCIATED DISORDERS The invention relates to the identification of new polypeptide and protein variants of fibroblast growth factor 21 (FGF21) that have improved pharmaceutical properties. Also disclosed are methods for treating FGF21-associated disorders, including metabolic conditions.... | 05/24/2012 |
| 20120125351 | DISINTEGRABLE ORAL FILMS A water soluble film that is disintegrable in the oral cavity to deliver an active agent is provided. The disintegrable film includes at least one water soluble polymer and an active agent. Also provided are methods for preparing the disintegrable oral film and for usin... | 05/24/2012 |
| 20120108657 | DISEASE-ASSOCIATED PROTEIN Disclosed are methods and compositions for early diagnosis, monitoring and treatment of retinal dystrophy, age-related macular degeneration, Bardet-Biedel syndrome, Bassen-kornzweig syndrome, best disease, choroidema, gyrate atrophy, congenital amourosis, refsun syndrom... | 05/03/2012 |
| 20120108523 | DISEASE-ASSOCIATED PROTEIN Disclosed are methods and compositions for early diagnosis, monitoring and treatment of retinal dystrophy, age-related macular degeneration, Bardet-Biedel syndrome, Bassen-kornzweig syndrome, best disease, choroidema, gyrate atrophy, congenital amourosis, refsun syndrom... | 05/03/2012 |
| 20120107340 | COMPOSITIONS FOR IMMUNISING AGAINST STAPHYLOCOCCUS AUREUS An effective Staphylococcus aureus vaccine may require several antigenic components, and so various combinations of S. aureus antigens are identified for use in immunisation. These polypeptides may optionally be used in combination with S. aureus sa... | 05/03/2012 |
| 20120107322 | IMMUNOGENIC AND THERAPEUTIC COMPOSITIONS FOR STREPTOCOCCUS PYOGENES Compositions for preventing and/or treating S. pyogenes infection which comprise one or more active agents. The active agents are SLO antigens, nucleic acid molecules encoding the SLO antigens, and/or antibodies which selectively bind to the SLO antigens.... | 05/03/2012 |
| 20120107306 | ANTIBODIES FOR EPIDERMAL GROWTH FACTOR RECEPTOR 3 (HER3) The present invention relates to antibodies or fragments thereof that target a conformational epitope of a HER receptor. In particular, the invention relates to antibodies or fragments thereof that target a conformational epitope of HER3 receptor and compositions and me... | 05/03/2012 |
| 20120083496 | ISOXAZOLE COMPOUND FOR THE TREATMENT OF CANCER The use of 5-(2,4-Dihydroxy-5-isopropyl-phenyl)-4-(4-morpholin-4-ylmethyl-phenyl)-isoxazole-3-carboxylic acid ethylamide or a tautomer thereof or a pharmaceutically acceptable salt or a hydrate or a solvate for the treatment of cancer of the bladder, the colon, the live... | 04/05/2012 |
| 20120082681 | ANTI-IL12RBETA1 ANTIBODIES AND THEIR USE IN TREATING AUTOIMMUNE AND INFLAMMATORY DISORDERS The present invention relates to antibodies that specifically bind to IL12Rβ1, the non-signal transducing chain of both the heterodimeric IL12 and IL23 receptors. The invention more specifically relates to specific antibodies that are IL12 and IL23 receptor antagonists... | 04/05/2012 |
| 20120071630 | Nucleic Acid and Amino Acid Sequences of Infectious Salmon Anaemia Virus and Their Use as Vaccines The present invention provides the use of nucleic acid sequences and/or amino acid sequences in the preparation of a vaccine for the protection of fish against infectious salmon anaemia virus. Specifically, such vaccines contain at least one nucleic acid sequence which ... | 03/22/2012 |
| 20120071514 | BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacolog... | 03/22/2012 |
| 20120071512 | 5-PYRIDIN-3-YL-1, 3-DIHYDRO-INDOL-2-ON DERIVATIVES AND THEIR USE AS MODULATORS OF ALDOSTERONE SYNTHASE AND/OR CYP11B1 The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacolog... | 03/22/2012 |
| 20120071479 | PYRAZINE DERIVATIVES AS ENAC BLOCKERS Compounds of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8 | |
| 20120070458 | ADJUVANTING MENINGOCOCCAL FACTOR H BINDING PROTEIN Factor H binding protein (fHBP) has been proposed for use in immunising against serogroup B meningococcus (‘MenB’). This antigen can be efficiently adsorbed to an aluminium hydroxyphosphate adjuvant by (i) ensuring that adsorption takes place at a pH which is equal ... | 03/22/2012 |
| 20120070457 | Polypeptides from neisseria meningitidis Polypeptides comprising Neisseria meningitidis amino acid sequences. Over 36000 meningococcal polypeptide sequences are disclosed. The invention also provides related polypeptides, nucleic acids, antibodies and methods. These can all be usedin medicine for treati... | 03/22/2012 |
| 20120053230 | TREATMENT OF NEUROLOGICAL DISORDERS BY dsRNA ADMINISTRATION The present invention relates to methods to treat neurological disorders comprising intrathecal injection of an effective amount of a double-stranded (ds) RNA into a subject in need, wherein the dsRNA inhibits the expression of a target gene and to pharmaceutical compos... | 03/01/2012 |
| 20120053161 | TOPICAL SOLUTION FORMULATIONS CONTAINING A CORTICOSTEROID AND A CYCLODEXTRIN Solution formulations containing a corticosteroid, cyclodextrin, and xanthan gum are disclosed. The formulations are intended for topical application to the eye, ear, or nose.... | 03/01/2012 |
| 20120045450 | METHOD FOR PREVENTING AND TREATING CANCER METASTASIS AND BONE LOSS ASSOCIATED WITH CANCER METASTASIS M-CSF antagonists are used to prepare compositions, including pharmaceutical compositions, for preventing or treating cancer metastasis and/or bone loss associated with cancer metastasis in a mammal.... | 02/23/2012 |
| 20120041052 | Compositions and Methods to Treat Muscular & Cardiovascular Disorders The present invention relates to a novel microRNA, mir-208-2, implicated in muscular and cardiovascular disorders. The present invention also relates to oligonucleotide therapeutic agents (antisense oligonucleotides and/or double stranded oligonucleotides such as dsRNA)... | 02/16/2012 |
| 20120039934 | ADJUVANT-SPARING MULTI-DOSE INFLUENZA VACCINATION REGIMEN An influenza vaccine is administered by a multi-dose regimen, in which (i) a first dose is administered with an adjuvant and (ii) a later dose is administered either without an adjuvant or with a different adjuvant. Thus the invention provides the benefits of a two-dose... | 02/16/2012 |
| 20120038073 | SPRAY DRYING METHODS AND RELATED COMPOSITIONS A method and apparatus are provided for atomizing a liquid under dispersal conditions suitable for spray drying at a commercial plant scale. In one embodiment, a liquid atomizer has a structural body adapted for connection with a spray dryer and a plurality of atomizing... | 02/16/2012 |
| 20120035174 | Salts of N-[6-cis-2,6-Dimethylmorpholin-4-yl)pyridine-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide Salts of N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridine-3-yl]-2-methyl-4′-(trifluoromethoxy)[1,1′-biphenyl]-3-carboxamide are prepared and characterized.... | 02/09/2012 |
| 20120035168 | N-((6-AMINO-PYRIDIN-3-YL)METHYL)-HETEROARYL-CARBOXAMIDES The invention relates to compound of the formula I in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments ... | 02/09/2012 |
| 20120034650 | Nucleic acid molecule of a biosynthetic cluster encoding non ribosomal peptide synthases and uses thereof The present invention relates to the provision of a polynucleotide comprising one or more functional fragments of a biosynthetic gene cluster involved in the production of a compound of formula (I) or (I′). The present invention also provides a method of preparing a c... | 02/09/2012 |
| 20120034262 | Bovine Herpes Virus-1 Compositions, Vaccines and Methods The disclosure relates generally to the treatment or prevention of disease in cattle. More particularly, the invention is directed to the production and use of modified bovine herpesvirus 1 (BHV-1) and their use in compositions and vaccines that protect cattle from BHV-... | 02/09/2012 |
| 20120034231 | COMPOSITIONS AND METHODS OF USE FOR THERAPEUTIC ANTIBODIES The present invention relates to antibodies that specifically bind to IL12Rβ1, the non-signal transducing chain of the heterodimeric IL12 receptor (together with IL12Rβ2 chain) as well as IL23 receptor (together with IL23Rα chain). The invention more specifically rel... | 02/09/2012 |
| 20120029084 | Topical Nepafenac Formulations Topical suspension compositions of nepafenac are disclosed. The compositions are especially suitable for topical ophthalmic administration.... | 02/02/2012 |
| 20120029053 | Short Interfering Ribonucleic Acid (siRNA) for Oral Administration Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands... | 02/02/2012 |
| 20120029052 | Short Interfering Ribonucleic Acid (siRNA) for Oral Administration Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands... | 02/02/2012 |
| 20120028969 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF The present invention provides compounds of formula (I); or pharmaceutically acceptable salts thereof, wherein the variables are defined as herein. The present invention provides a method for manufacturing th... | 02/02/2012 |
| 20120027801 | POLYPEPTIDES FROM NEISSERIA MENINGITIDIS Various specific meningococcal proteins are disclosed. The invention provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by meningococcus, such as bacterial me... | 02/02/2012 |
| 20110282053 | Organic Compounds A process for preparing compounds of formula I or a solvate or hydrate thereof, where R, R1, R2, R3 and R5 have the meanings as indicated in the specification. Such... | 11/17/2011 |
| 20110281845 | ORGANIC COMPOUNDS The present disclosure relates to XIAP inhibitor compounds of the formula I. ... | 11/17/2011 |
| 20110281751 | CELL SURFACE DISPLAY OF POLYPEPTIDE ISOFORMS BY STOP CODON READTHROUGH The present invention inter alia pertains to a method for generating or selecting a eukaryotic host cell expressing a desired level of a polypeptide of interest, comprising:
| |
| 20120022139 | Short Interfering Ribonucleic Acid (siRNA) for Oral Administration Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands... | 01/26/2012 |
| 20110277752 | RECEPTACLE FOR AN AEROSOLIZABLE PHARMACEUTICAL FORMULATION An article for storing a pharmaceutical formulation. In one or more embodiments, the present invention comprises a receptacle (125) for an aerosolizable formulation, the receptacle having a wall thickness of between about 100-235 microns, wherein the receptacle i... | 11/17/2011 |