William F. Semple, a dentist, was awarded the first US Patent on chewing gum in 1869. His recipe contained powdered chalk.
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| Application No. | Application Title | Issue Date |
| 20100280258 | METHODS FOR THE PREPARATION OF AMPHILLIC NITROGEN CONTAINING IMIDAZOLINIUM DERIVATIVE COMPOUNDS The disclosure provides new methods for preparing nitrogen-containing amphiphiles and their use in the preparation of liposomes and other lipid-containing carriers of pharmaceutical substances, including nucleic acids used in gene therapy.... | 11/04/2010 |
| 20100086584 | VACCINE COMPOSITIONS OF M2e, HA0 AND BM2 MULTIPLE ANTIGENIC PEPTIDES The present disclosure generally relates to a composition comprising one or more peptides selected from influenza virus antigenic peptides M2e, HA0, BM2 and a M2e-BM2 fusion peptide in a composition with a cationic liposome delivery vehicle, and the use of... | 04/08/2010 |
| 20090263423 | Enhancement of an Immune Response by Administration of a Cationic Lipid-DNA Complex (CLDC) This invention relates to a method for vaccination which is effective for eliciting an enhanced antigen-specific immune response in a mammal, fish or bird. The method is particularly effective for protecting a mammal, fish or bird from a disease including cancer, a dise... | 10/22/2009 |