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| Application No. | Application Title | Issue Date |
| 20080304531 | Integrated broadband quantum cascade laser A broadband, integrated quantum cascade laser is disclosed, comprising ridge waveguide quantum cascade lasers formed by applying standard semiconductor process techniques to a monolithic structure of alternating layers of claddings and active region layers. The resultin... | 12/11/2008 |
| 20080304207 | LOW TEMPERATURE DOUBLE-LAYER CAPACITORS Double-layer capacitors capable of operating at extremely low temperatures (e.g., as low as −75° C.) are disclosed. Electrolyte solutions combining a base solvent (e.g., acetonitrile) and a cosolvent are employed to lower the melting point of the base electrolyte. Ex... | 12/11/2008 |
| 20080304044 | HIGH-RESOLUTION THREE-DIMENSIONAL IMAGING RADAR A three-dimensional imaging radar operating at high frequency e.g., 670 GHz, is disclosed. The active target illumination inherent in radar solves the problem of low signal power and narrow-band detection by using submillimeter heterodyne mixer receivers. A submillimete... | 12/11/2008 |
| 20080289710 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 11/27/2008 |
| 20080286255 | TREATMENT FOR EYE DISORDER The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thick... | 11/20/2008 |
| 20080281090 | Microfluidic Chemical Reaction Circuits New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.... | 11/13/2008 |
| 20080280583 | Submillimeter wave heterodyne receiver In an embodiment, a submillimeter wave heterodyne receiver includes a finline ortho-mode transducer comprising thin tapered metallic fins deposited on a thin dielectric substrate to separate a vertically polarized electromagnetic mode from a horizontally polarized elect... | 11/13/2008 |
| 20080279954 | Method of preparing a supramolecular complex containing a therapeutic agent and a multi-dimensional polymer network A method of preparing a supramolecular complex containing at least one therapeutic agent and a multi-dimensional polymer network is described. A supramolecular complex prepared by a method of the invention is described. A method of treatment by administering a therapeut... | 11/13/2008 |
| 20080277007 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 11/13/2008 |
| 20080277005 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 11/13/2008 |
| 20080274493 | APPARATUS AND METHODS FOR CONDUCTING ASSAYS AND HIGH THROUGHPUT SCREENING The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention inc... | 11/06/2008 |
| 20080268505 | Method for creating polynucleotide and polypeptide sequences The invention provides methods for evolving a polynucleotide toward acquisition of a desired property. Such methods entail incubating a population of parental polynucleotide variants under conditions to generate annealed polynucleotides comprising heteroduplexes. The he... | 10/30/2008 |
| 20080264863 | Microfluidic Sieve Valves Sieve valves for use in micorfluidic device are provided. The valves are useful for impeding the flow of particles, such as chromatography beads or cells, in a microfluidic channel while allowing liquid solution to pass through the valve. The valves find particular use ... | 10/30/2008 |
| 20080258841 | Wireless acoustic-electric feed-through for power and signal transmission An embodiment provides electrical energy from a source on one side of a medium to a load on the other side of the medium, the embodiment including a first piezoelectric to generate acoustic energy in response to electrical energy from the source, and a second piezoelect... | 10/23/2008 |
| 20080255439 | Microfabricated Neural Probes and Methods of Making Same An embodiment of the invention provides a neural probe (100) containing a plurality of nanoscale recording electrodes. The recording electrodes have a width of 1 micron or less and a distance between adjacent recording electrodes is 10 microns or less. Another em... | 10/16/2008 |
| 20080245430 | PLASMON ASSISTED CONTROL OF OPTOFLUIDICS A method of microfluidic control via localized heating includes providing a microchannel structure with a base region that is partially filled with a volume of liquid being separated from a gas by a liquid-gas interface region. The base region includes one or more physi... | 10/09/2008 |
| 20080249281 | Degradable polymers and methods of preparation thereof The present invention provides polymers which substantially degrade in the presence of one or more triggers, preferably light energy or hydrogen peroxide, but does not substantially degrade in the absence of one or more triggers.... | 10/09/2008 |
| 20080236669 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTMES A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 10/02/2008 |
| 20080234217 | Inhibitor Nucleic Acids The present invention provides methods and compositions for attenuating expression of a target gene in vivo. In general, the method includes administering RNAi constructs (such as small-interfering RNAs (i.e., siRNAs) that are targeted to particular mRNA sequences, or n... | 09/25/2008 |
| 20080233744 | CARBON NANOTUBE SWITCHES FOR MEMORY, RF COMMUNICATIONS AND SENSING APPLICATIONS, AND METHODS OF MAKING THE SAME Switches having an in situ grown carbon nanotube as an element thereof, and methods of fabricating such switches. A carbon nanotube is grown in situ in mechanical connection with a conductive substrate, such as a heavily doped silicon wafer or an SOI wafer. The carbon n... | 09/25/2008 |
| 20080228242 | METHOD AND SYSTEM FOR TRAINING A VISUAL PROSTHESIS A method for training a visual prosthesis includes presenting a non-visual reference stimulus corresponding to a reference image to a visual prosthesis patient. Training data sets are generated by presenting a series of stimulation patterns to the patient through the vi... | 09/18/2008 |
| 20080220216 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 09/11/2008 |
| 20080214488 | TRIGGERED RNAi The present application relates to methods and compositions for triggering RNAi. Triggered RNAi is highly versatile because the silencing targets are independent of the detection targets. In some embodiments, a method of silencing a target gene is provided. The method c... | 09/04/2008 |
| 20080211061 | Method For the Fabrication of GaAs/Si and Related Wafer Bonded Virtual Substrates A method of making a virtual substrate includes providing a device substrate of a first material containing a device layer of a second material different from the first material located over a first side of the device substrate, implanting ions into the device substrate... | 09/04/2008 |
| 20080210321 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 09/04/2008 |
| 20080210320 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 09/04/2008 |
| 20080210319 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 09/04/2008 |
| 20080210322 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 09/04/2008 |
| 20080206803 | Metabolic genes and related methods and compositions Certain aspects of the invention provide nucleic acid constructs that can be used to cause a cell to be dependent on a particular enzymatic activity or on the presence of a particular small molecule. Certain aspects of the invention also provide methods for cloning gene... | 08/28/2008 |
| 20080206759 | Gene regulatory networks and methods of interdiction for controlling the differentiation state of a cell The invention provides a method of modulating a regulatory state of a cell. The method consists of: (a) identifying a point of interdiction within a cis regulatory network specifying a genetic regulatory architecture of a cell, and (b) introducing into a progenitor cell... | 08/28/2008 |
| 20080190830 | MICROFLUIDIC SEPARATION DEVICE AND METHOD OF MAKING SAME A device and method for making a microfluidic separation device. A microfluidic separation device could include a microfluidic column having an inlet, the microfluidic column being configured to hold a first fluid and the microfluidic column including a porous portion, ... | 08/14/2008 |
| 20080185341 | Water treatment by dendrimer-enhanced filtration Described herein are compositions and methods useful for the purification of aqueous fluids using dendritic macromolecules. The process involves using dendritic macromolecules (dendrimers) to bind to or chemically transform solutes, and a filtration step to produce flui... | 08/07/2008 |
| 20080182273 | Microfluidic free interface diffusion techniques A static fluid and a second fluid are placed into contact along a microfluidic free interface and allowed to mix by diffusion without convective flow across the interface. In accordance with one embodiment of the present invention, the fluids are static and initially po... | 07/31/2008 |
| 20080179514 | AMBIENT PRESSURE PYROELECTRIC ION SOURCE FOR MASS SPECTROMETRY A compact, low power ambient pressure pyroelectric ionization source. The source can be constructed using a z-cut lithium niobate or lithium tantalate crystal with an attached resistive heater mounted in front of the atmospheric pressure inlet of an ion trap mass spectr... | 07/31/2008 |
| 20080177196 | PROSTHETIC DEVICES AND METHODS AND SYSTEMS RELATED THERETO The present invention relates to systems and methods for controlling neural prosthetic devices and electrophysiological recording equipment, and for using the same in clinical operation. Various embodiments of the invention are directed to an algorithm for autonomously ... | 07/24/2008 |
| 20080176211 | Microfabricated Cell Sorter The invention provides a microfabricated device for sorting cells based on a desired characteristic, for example, reporter-labeled cells can be sorted by the presence or level of reporter on the cells. The device includes a chip having a substrate into which is microfab... | 07/24/2008 |
| 20080173833 | ELECTRICALLY ACTUATED VALVES MADE FROM SHAPE MEMORY ALLOY WIRES EMBEDDED IN ELASTOMER Microfluidic valves constructed from elastomeric materials as the valve body components and employing shape memory alloy in wire form as the valve actuator. Various configurations of individual valves having both normally open and normally closed states are described. A... | 07/24/2008 |
| 20080173365 | MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first e... | 07/24/2008 |
| 20080168320 | Codes For Limited Magnitude Asymetric Errors In Flash Memories Error correction is tailored for the use of an ECC for correcting asymmetric errors with low magnitude in a data device, with minimal modifications to the conventional data device architecture. The technique permits error correction and data recovery to be performed wit... | 07/10/2008 |
| 20080160609 | OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES Methods for producing modified polypeptides containing amino acid analogues are disclosed. The invention further provides purified dihydrofolate reductase polypeptides, produced by the methods of the invention, in which the methionine residues have been replaced with ho... | 07/03/2008 |
