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| Application No. | Application Title | Issue Date |
| 20120130676 | IN SITU TUBING MEASUREMENTS FOR INFUSION PUMPS An infusion pump having a tubing clamping section including a movable and a stationary portion. The infusion pump includes at least one sensor for detecting a contact length of tubing within the movable and/or the stationary portion. The infusion pump includes a shuttle... | 05/24/2012 |
| 20120128653 | PROCESS FOR MAKING DRY AND STABLE HEMOSTATIC COMPOSITIONS Described is a process for making a dry and stable hemostatic composition, said process comprising
| 05/24/2012 |
| 20120108513 | PURIFICATION METHOD FOR DIVALENT CATION BINDING PROTEINS ON ANION EXCHANGE RESIN The present invention relates to a method for the purification of divalent cation binding proteins with high purity on an anion exchange resin material, to divalent cation binding proteins obtainable by said method, and to a kit comprising means for carrying out said me... | 05/03/2012 |
| 20120105850 | CASSETTE-BASED METHOD AND APPARATUS FOR MEASURING THE PRESENCE AND CONCENTRATION OF PHARMACEUTICAL SUBSTANCES IN A MEDICAL FLUID A medical fluid delivery system includes a medical fluid delivery machine including a light source configured to generate a light beam; a polarizer configured to receive the light beam and to allow a portion of the light beam within the medical fluid to be transmitted t... | 05/03/2012 |
| 20120083729 | Peritoneal dialysis machine A method for operating a dialysis cassette including a flexible membrane that covers a pump chamber includes applying a vacuum about a piston head and sucking the flexible membrane of the dialysis cassette onto the piston head; mechanically retracting the piston head al... | 04/05/2012 |
| 20120083446 | NOVEL ALBUMIN-FREE FACTOR VIII FORMULATIONS An albumin-free Factor VIII formulation comprising, 4% to 10% of a bulking agent selected from the group consisting of mannitol, glycine and alanine; 1% to 4% of a stabilizing agent selected from the group consisting of sucrose, trehalose, raffinose, and arginine; 1 mM ... | 04/05/2012 |
| 20120082987 | Transgenic Non-Human Animals Expressing Human Blood Clotting Factors and Uses Thereof The present invention relates, in general, to development of non-human transgenic animals expressing a human blood clotting factor, such as Factor VIII, Factor VII, Factor IX and von Willebrand factor. The invention further provides methods of detecting immunogenic even... | 04/05/2012 |
| 20120071816 | AUTOMATED DIALYSIS SYSTEM INCLUDING TOUCH SCREEN CONTROLLED MECHANICALLY AND PNEUMATICALLY ACTUATED PUMPING A peritoneal dialysis system includes: a hardware unit including a piston having a contact surface, a pneumatic source for supplying a negative pressure, a stepper motor, a controller including a processor and memory programmed to control the pneumatic source and the st... | 03/22/2012 |
| 20120071815 | DRAIN AND FILL LOGIC FOR AUTOMATED PERITONEAL DIALYSIS The present system and method in one embodiment limit a maximum instantaneous peritoneal volume to a comfortable level, while allowing the dialysis machine to advance to fill a prescribed volume whenever the drain ends after a minimum drain percentage has been attained.... | 03/22/2012 |
| 20120071747 | USE OF VENTRICULAR ENLARGEMENT RATE IN INTRAVENOUS IMMUNOGLOBULIN TREATMENT OF ALZHEIMERS DISEASE The present invention relates to the use of MRI monitoring of ventricular enlargement rate as an objective measure for the purpose of assessing disease progression in patients suffering from Alzheimer's disease and for the purpose of determining therapeutic effectivenes... | 03/22/2012 |
| 20120070498 | Submicron Particles of Antineoplastic Agents The present invention is concerned with the formation of submicron particles of an antineoplastic agent, particularly paclitaxel, by precipitating the antineoplastic agent in an aqueous medium to form a pre-suspension followed by homogenization. Surfactants with phospho... | 03/22/2012 |
| 20120067805 | DIALYSIS SYSTEM METHOD HAVING SUPPLY CONTAINER AUTOCONNECTION A dialysis system is disclosed including an autoconnection mechanism. The autoconnection mechanism in an embodiment is configured such that (i) a tip protector remover is translated in a first direction towards a plurality of supply line connectors, (ii) the tip protect... | 03/22/2012 |
| 20120053555 | ASSEMBLY TO FACILITATE USER RECONSTITUTION A reconstitution assembly includes a housing including a lower sleeve and an upper sleeve, including a first container and a second container disposed vertically opposite the first container. A transfer set assembly is disposed within the housing between the first conta... | 03/01/2012 |
| 20120053113 | MANUFACTURE OF INTER-ALPHA-INHIBITOR (IaIp) FROM PLASMA The present invention provides compositions and pharmaceutical formulations of IaIp derived from plasma. Also provided are methods for the manufacture of the IaIp compositions and formulations, as well as method for the treatment of diseases associated with IaIp dysfunc... | 03/01/2012 |
| 20120045364 | MULTI-PART SUBSTITUTION INFUSION FLUIDS AND MATCHING ANTICOAGULANTS A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolytes but without divalent cations and a second solution co... | 02/23/2012 |
| 20120043279 | SYSTEMS AND METHODS FOR PRIMING SORBENT-BASED HEMODIALYSIS A method for priming a hemodialysis treatment includes (i) providing a sorbent cartridge for cleaning spent dialysate fluid returning from a dialyzer: (ii) preparing a batch of dialysate in a quantity commensurate with being recycled through the sorbent cartridge multip... | 02/23/2012 |
| 20120041416 | DRUG DELIVERY DEVICE FOR FLUID RESTRICTED PATIENTS A syringe assembly for connecting to an intravenous (“IV”) line includes: a syringe barrel having an actuation end and a discharge end; a syringe plunger moveable within the syringe barrel, the syringe plunger including a plunger head connected to a plunger arm; a s... | 02/16/2012 |
| 20120040379 | METHODS FOR DIFFERENTIATING PLASMA- DERIVED PROTEIN FROM RECOMBINANT PROTEIN IN A SAMPLE The present invention relates, in general, to methods for detecting and quantitating plasma-derived protein and recombinant protein in a sample based on the difference in protein glycosylation, when the plasma protein and the recombinant protein are essentially the same... | 02/16/2012 |
| 20120037558 | METHOD AND COMPOSITION FOR REMOVING UREMIC TOXINS IN DIALYSIS PROCESSES Methods and devices for providing dialysis treatment are provided. The device includes a resin bed including zirconium phosphate, zirconium oxide, and urease.... | 02/16/2012 |
| 20120037550 | HEMODIALYSIS SYSTEM WITH CASSETTE AND PINCH CLAMP A hemodialysis system includes (i) blood tubing; (ii) a peristaltic blood pump contacting the blood tubing to pump blood through the blood tubing; (iii) a dialyzer in fluid communication with the blood tubing; (iv) first and second peristaltic dialysate pumps; (v) a dia... | 02/16/2012 |
| 20120035534 | DIALYSIS SYSTEM INCLUDING WIRELESS PATIENT DATA AND TRENDING AND ALERT GENERATION A peritoneal dialysis system includes an automated peritoneal dialysis (“APD”) machine including a logic implementer and a wireless interface receiver. The system also includes at least one of a scale or a blood pressure monitor including a wireless interface transm... | 02/09/2012 |
| 20120035533 | PERITONEAL DIALYSIS MACHINE TOUCH SCREEN USER INTERFACE A peritoneal dialysis machine including a membrane pump and a touch screen display that includes a mode-indicating portion and an operation-descriptive portion, the mode-indicating portion having a plurality of touch sensitive indicia each indicating one of a plurality ... | 02/09/2012 |
| 20120035344 | NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE The invention relates to materials and methods of conjugating a water soluble polymer to an oxidized carbohydrate moiety of a therapeutic protein comprising contacting the oxidized carbohydrate moiety with an activated water soluble polymer under conditions that allow c... | 02/09/2012 |
| 20120035110 | METHOD OF PRODUCING RECOMBINANT HIGH MOLECULAR WEIGHT vWF IN CELL CULTURE Among other aspects, the present invention relates to cell culture conditions for producing high molecular weight vWF, in particular, highly multimericWF with a high specific activity and ADAMTS13 with a high specific activity. The cell culture conditions of the present... | 02/09/2012 |
| 20120034674 | METHOD OF PRODUCING RECOMBINANT ADAMTS13 IN CELL CULTURE Among other aspects, the present invention relates to cell culture conditions for producing high molecular weight vWF, in particular, highly multimericWF with a high specific activity and ADAMTS13 with a high specific activity. The cell culture conditions of the present... | 02/09/2012 |
| 20120031826 | HEMODIALYSIS SYSTEM HAVING CLAMPING MECHANISM FOR PERISTALTIC PUMPING A hemodialysis system including (i) an instrument; (ii) first and second peristaltic dialysate pumps operated by the instrument; (iii) a cassette including a rigid structure and first and second dialysate pumping tubes carried by the rigid structure; and (iv) a mechanis... | 02/09/2012 |
| 20120029324 | THERAPY PREDICTION AND OPTIMIZATION FOR RENAL FAILURE BLOOD THERAPY, ESPECIALLY HOME HEMODIALYSIS A method of predicting serum phosphorus concentrations in a patient during hemodialysis includes measuring serum phosphorus concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and p... | 02/02/2012 |
| 20120028901 | TFPI INHIBITORS AND METHODS OF USE The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood ... | 02/02/2012 |
| 20110281938 | APTAMERS TO TISSUE FACTOR PATHWAY INHIBITOR AND THEIR USE AS BLEEDING DISORDER THERAPEUTICS The invention relates generally to the field of nucleic acids and more particularly to aptamers that bind to TFPI, which are useful as therapeutics in and diagnostics of bleeding disorders and/or other diseases or disorders in which TFPI has been implicated. In addition... | 11/17/2011 |
| 20120022442 | DIALYSIS SYSTEM AND MACHINE HAVING THERAPY PRESCRIPTION RECALL In an embodiment, an automated peritoneal dialysis (“APD”) machine includes at least one pump, a logic implementer storing a plurality of therapy prescriptions by which to operate the at least one pump, each therapy prescription pre-approved for a particular patient... | 01/26/2012 |
| 20120022441 | MEDICAL FLUID PUMP VALVE INTEGRITY TEST METHODS AND SYSTEMS A valve integrity method for a medical fluid pump includes pumping fluid into the medical fluid pump while an outlet valve is closed and an inlet valve is open, closing the inlet valve while the outlet valve is closed, attempting to pump fluid out of the medical fluid p... | 01/26/2012 |
| 20120022440 | DIALYSIS SYSTEM HAVING DISPOSABLE CASSETTE A dialysis system includes a dialysis instrument and a disposable cassette. The dialysis instrument includes three pump actuators. The disposable cassette includes three dialysate pump chambers. The three dialysate pump chambers are positioned and arranged to operate wi... | 01/26/2012 |
| 20120021058 | PROCESS FOR MAKING DRY AND STABLE HEMOSTATIC COMPOSITIONS Described is a process for making a dry and stable hemostatic composition, said process comprising
| 01/26/2012 |
| 20120020973 | CHIMERIC OSPA GENES, PROTEINS, AND METHODS OF USE THEREOF The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while ret... | 01/26/2012 |
| 20120018378 | RENAL FAILURE THERAPY MACHINES AND METHODS INCLUDING CONDUCTIVE AND CONVECTIVE CLEARANCE A renal failure therapy method includes causing therapy fluid to flow to a renal failure therapy filter, directing at least twenty-five percent of the therapy fluid to the renal failure therapy filter to perform conductive clearance, and using the renal therapy failure ... | 01/26/2012 |
| 20110275984 | CUSTOMIZABLE PERSONAL DIALYSIS DEVICE HAVING EASE OF USE AND THERAPY ENHANCEMENT FEATURES A peritoneal dialysis machine includes an enclosure; dialysate pump located within the enclosure; a graphical user interface allowing a patient to program a treatment including at least one patient fill performed by the dialysate pump, at least one dwell, and at least o... | 11/10/2011 |
| 20110274758 | MICROSPHERE-BASED COMPOSITION FOR PREVENTING AND/OR REVERSING NEW-ONSET AUTOIMMUNE DIABETES AS-oligonucleotides are delivered in microsphere form in order to induce dendritic cell tolerance, particularly in the non-obese-diabetic (NOD) mouse model. The microspheres incorporate antisense (AS) oligonucleotides. A process includes using an antisense approach to r... | 11/10/2011 |
| 20110266221 | FLOW BALANCING SYSTEM AND METHOD, ESPECIALLY FOR CITRATE A renal failure therapy system includes a blood pump; a citrate pump; and a control unit configured to automatically control the blood pump and the citrate pump to achieve a citrate flowrate that is based on at least a blood flowrate.... | 11/03/2011 |
| 20110264042 | CONDUCTIVE POLYMER MATERIALS AND APPLICATIONS THEREOF INCLUDING MONITORING AND PROVIDING EFFECTIVE THERAPY A coupler includes a conductive polymer material that is so constructed and arranged to join tubing, wherein the conductive polymer material includes a conductive polymer component selected from the group consisting of polyaniline, polypyrrole, polythiophenes, polyethyl... | 10/27/2011 |
| 20110264025 | REGIONAL CITRATE ANTICOAGULATION A system or method automates and optimizes citrate anticoagulant supplementation in a blood filtration circuit during CRRT. A processor-based control system interfaces with a blood filtration circuit to detect patient blood flow into the circuit, detect fluid loss throu... | 10/27/2011 |
