US Patent Application 20120015911 - METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES
Inventors
AssigneeUS Classes514/150, Acyclic nitrogen double bonded to acyclic nitrogen, acyclic nitrogen triple bonded to acyclic nitrogen or azide DOAI514/182, Oxygen single bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system514/292, Plural ring nitrogens in the tricyclo ring system514/315, Piperidines514/395, Chalcogen or nitrogen bonded directly at 1-, 2- or 3-position of the diazole ring by nonionic bonding514/423, C=X bonded directly to the five-membered hetero ring by nonionic bonding (X is chalcogen)514/438, The hetero ring is five-membered514/444, Additional hetero ring514/471, Nitrogen containing514/550, Z radical contains sulfur or halogen514/562, Sulfur nonionically bonded514/659, Alicyclic ring or ring system and amino nitrogen are attached indirectly by an acyclic carbon or acyclic chain534/826, Plural sulfonic acid groups bonded directly to the same bicyclo ring system (-(0=)S(=0)-OH, wherein H of the -OH may be replaced by the ammonium ion or a Group IA or IIA light metal)546/85, The six-membered hetero ring shares ring members with the five-membered cyclo only (e.g., pyrido-indoles, etc.)546/242, Chalcogen bonded directly to ring carbon of the piperidine ring546/248, Chalcogen attached indirectly to the piperidine ring by nonionic bonding548/307.1, The chalcogen is sulfur548/528, Polycyclo carbocyclic ring system having at least three cyclos549/59, Additional hetero ring containing549/75, Chalcogen attached indirectly to the hetero ring by nonionic bonding549/495, Chalcogen attached indirectly to the hetero ring by acyclic nonionic bonding560/150, Sulfonyl or sulfinyl in acid moiety562/100Polycyclo alicyclic ring system attached directly or indirectly to the sulfonate group by nonionic bondingInternational ClassesA61K 31/655A61K 31/437 A61K 31/4462 A61K 31/4184 A61K 31/40 A61K 31/381 A61K 31/341 A61K 31/22 A61K 31/195 A61K 31/13 C07C 245/10 C07D 471/04 C07D 211/96 A61K 31/4458 C07D 235/28 C07D 207/46 C07D 409/06 C07D 333/20 C07D 307/66 C07C 317/28 C07C 309/23 C07D 307/22 A61P 43/00 A61P 25/28 A61P 25/00 A61P 27/02 A61P 3/10 A61K 31/56 Abstract textMethods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease. |
| ||||||||||||||
