US Patent Application 20100069630 - NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
Inventors
AssigneesUS Classes544/162, Nitrogen attached directed or indirectly to morpholine ring by nonionic bonding546/244, Nitrogen attached directly to the piperidine ring by nonionic bonding548/326.5, Nitrogen attached directly to the diazole ring by nonionic bonding564/158, Hydroxy, bonded directly to carbon, or ether containing (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)549/505, Plural double bonds between ring members of the hetero ring548/543, Chalcogen bonded directly to a ring carbon of the five-membered hetero ring which is adjacent to the ring nitrogen (e.g., 2-pyrrolidones, etc.)549/74Nitrogen attached indirectly to the hetero ring by nonionic bondingAttorney, Agent or FirmForeign Documents
International ClassesC07D 295/00C07D 211/98 C07D 233/44 C07C 233/00 C07D 307/02 C07D 207/46 C07D 333/20 Issued Patent Number:8053435Abstract textThe present invention discloses novel naphthalenyloxypropenyl derivatives useful for inhibiting the enzyme activity of histone deacetylase, leading effective suppression of cancer cell proliferation. |
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