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US Patent Application 20100069378 - SUBSTITUTED INDANYL SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS

Application 20100069378 Filed on July 25, 2007. Published on March 18, 2010

Inventors

Assignee

US Classes

514/230.5, Bicyclo ring system having the six-membered hetero ring as one of the cyclos (e.g., 1,4-benzoxazines, etc.)544/398, Chalcogen attached indirectly to the piperazine ring by nonionic bonding544/376, Bicyclo ring system having the additional hetero ring as one of the cyclos544/368, The five-membered hetero ring is one of the cyclos in a polycyclo ring system564/81, Hydrazine containing548/155, Tetramisole per se or salt thereof (including hydrogenated)544/105, Bicyclo ring system having the oxazine ring as one of the cyclos (e.g., benzoxazines, etc.)514/255.03, Carbocyclic ring bonded directly to the piperazine ring514/252.13, Additional hetero ring attached directly or indirectly to the piperazine ring by nonionic bonding514/254.02, The additional five-membered hetero ring also has chalcogen as a ring member514/602, Q contains benzene ring514/368Ring nitrogen is shared by the cyclos of the bicyclo ring system (e.g., tetramisole, etc.)

Attorney, Agent or Firm

Foreign Documents

  • 06380220.1 EP 07/31/2006

International Classes

A61K 31/18
C07D 295/12
C07D 409/12
C07D 513/04
C07C 311/21
C07D 413/12
A61K 31/4965
A61K 31/496
A61K 31/429
A61K 31/538
A61P 3/00
A61P 25/00
A61P 25/22
A61P 25/24
A61P 25/18
A61P 25/28


Abstract text


The present invention refers to new indanyl sulphonamide compounds with general formula (I), as well as to their preparation procedure, their application as medicine and the pharmaceuticals composition which they are made up of. The new compounds of formula (I) show affinity for 5-HT6 receptors and are, therefore, effective for treating diseases mediated by these receptors.

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