US Patent Application 20100068139 - Methods of radiofluorination of biologically active vectors
InventorsUS Classes424/1.69, Attached to peptide or protein of 2+ amino acid units (e.g., dipeptide, folate, fibrinogen, transferrin, sp. enzymes); derivative thereof530/345, Chemical aftertreatment, e.g., acylation, methylation, etc.564/301, Acyclic564/197, The compound is acyclic564/149, Substituent Q contains benzene ring568/495, Halogen containing564/199, Carbonyl in substituent Q568/308, Benzene ring containing568/425, Benzene ring containing530/331, Tripeptides, e.g., tripeptide thyroliberin (TRH), melanostatin (MIF), etc.530/317, Cyclic peptides530/300PEPTIDES OF 3 TO 100 AMINO ACID RESIDUESAttorney, Agent or FirmForeign Documents
International ClassesA61K 51/08C07K 1/13 C07C 239/00 C07C 237/02 C07C 243/10 C07C 47/00 C07C 233/01 C07C 49/04 C07C 47/02 C07K 5/08 C07K 2/00 Abstract textThe invention relates to conjugates of formula (V) or (VI): wherein X is —CO—NH—, —NH—, —O—, —NHCONH—, or —NHCSNH—; their use as radiopharmaceuticals, processes for their preparation, and synthetic intermediates used in such processes. |
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