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US Patent Application 20100063075 - Aryl-quinazoline/aryl-2amino-phenyl methanone derivatives

Application 20100063075 Filed on October 15, 2009. Published on March 11, 2010

Inventors

US Classes

514/266.31, Carbocyclic ring bonded directly to a ring carbon of the quinazoline ring system544/286, Chalcogen bonded directly at 2-position564/323, Amino nitrogen attached to aryl ring or ring system by an acyclic carbon or chain514/648Two aryl rings or aryl ring systems bonded directly to the same acyclic carbon

Attorney, Agent or Firm

Foreign Documents

  • 0230015.0 GB 12/23/2002

International Classes

A61K 31/517
C07D 239/72
C07C 211/00
A61K 31/135
A61P 19/00


Abstract text


A compound of formula (1): wherein R1, R2, R3 and Y are as defined herein, or a pharmaceutically-acceptable and -cleavable ester, or acid addition salt thereof, useful for promoting the release of parathyroid hormone, e.g. for preventing or treating bone conditions which are associated with increased calcium depletion or resorption or in which stimulation of bone formation and calcium fixation in the bone is desirable.

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