US Patent Application 20100062019 - NEW VACCINE FORMULATIONS
InventorsUS Classes424/209.1, Orthomyxoviridae (e.g., influenza virus, fowl plague virus, etc.)424/258.1, Salmonella (e.g., Salmonella typhimurium, etc.)424/204.1, Virus or component thereof424/229.1, Herpetoviridae (e.g., herpesvirus, Marek`s disease virus, laryngotracheitis virus, infectious bovine rhinotracheitis virus (IBR), infectious pustular vulvovaginitis virus, bovine herpes virus type 1, Aujeszky`s disease virus, feline rhinotracheitis virus, feline herpes virus, etc.)424/222.1, Infectious bronchitis virus (IBV)424/221.1, Coronaviridae (e.g., neonatal calf diarrhea virus, feline infectious peritonitis virus, canine coronavirus, etc.)424/253.1, Bordetella (e.g., Bordetella bronchiseptica, etc.)424/264.1, Mycoplasma424/234.1Bacterium or component thereof or substance produced by said bacterium (e.g., Legionella, Borrelia, Anaplasma, Shigella, etc.)Attorney, Agent or FirmInternational ClassesA61K 39/145A61K 39/112 A61K 39/12 A61K 39/00 A61K 39/215 A61K 39/10 A61K 39/02 A61P 37/04 A61P 31/08 Abstract textThe present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified or weakly purified. The emulsion of the present invention can act as vehicle for the delivery of a pharmaceutical composition comprising at least one immunogen and, in particular, an immunogen selected from the group comprising an inactivated pathogen, an attenuated pathogen, a subunit, a recombinant expression vector, and a plasmid or combinations thereof. In one embodiment, the present invention provides for an injectable oil-in-water (O/W) emulsion comprising:
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