US Patent Application 20100047277 - VIROSOMES, METHODS OF PREPARATION, AND IMMUNOGENIC COMPOSITIONS
InventorsUS Classes424/208.1, Immunodeficiency virus (e.g., HIV, etc.)424/204.1, Virus or component thereof424/207.1, Retroviridae (e.g., feline leukemia virus, bovine leukemia virus, avian leukosis virus, equine infectious anemia virus, Rous sarcoma virus, HTLV-I, etc.)424/209.1, Orthomyxoviridae (e.g., influenza virus, fowl plague virus, etc.)424/211.1, Paramyxoviridae (e.g., parainfluenza virus, respiratory syncytial virus, rinderpest virus, Sendai virus, canine tracheobronchitis virus, turkey rhinotracheitis virus, etc.)424/218.1, Togaviridae or Flaviviridae, except hepatitis C virus (e.g., yellow fever virus, bovine viral diarrhea virus, dengue virus, equine viral arteritis virus, equine encephalitis virus, Japanese B encephalitis virus, Sindbis virus, flavivirus, etc.)424/221.1, Coronaviridae (e.g., neonatal calf diarrhea virus, feline infectious peritonitis virus, canine coronavirus, etc.)424/224.1, Rhabdoviridae (e.g., rabies virus, vesicular stomatitis virus, etc.)424/229.1, Herpetoviridae (e.g., herpesvirus, Marek`s disease virus, laryngotracheitis virus, infectious bovine rhinotracheitis virus (IBR), infectious pustular vulvovaginitis virus, bovine herpes virus type 1, Aujeszky`s disease virus, feline rhinotracheitis virus, feline herpes virus, etc.)424/230.1, Cytomegalovirus, varicella or herpes zoster virus, or Epstein-Barr virus435/5, Involving virus or bacteriophage435/455Introduction of a polynucleotide molecule into or rearrangement of nucleic acid within an animal cellAttorney, Agent or FirmInternational ClassesA61K 39/12A61K 39/21 A61K 39/145 A61K 39/155 A61K 39/215 A61K 39/205 A61K 39/245 A61K 39/25 C12Q 1/70 C12N 15/00 A61P 31/12 Abstract textBriefly described, virosomes, methods of preparing virosomes, immunogenic compositions that include virosomes, and methods of eliciting an immune response using immunogenic compositions that include virosomes are described herein. A virosome can include at least one viral surface envelope glycoprotein expressed on the surface of the virosome. The virosome can also optionally include at least one adjuvant molecule expressed on the surface of the virosome. |
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