US Patent Application 20100021548 - USE OF MICROPARTICLES WITH ADSORBED ANTIGEN TO STIMULATE IMMUNE RESPONSES

Application 20100021548 Filed on October 6, 2009. Published on January 28, 2010

Inventors

Assignee

Novartis Vaccines and Diagnostics, Inc.

US Classes

424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/208.1, Immunodeficiency virus (e.g., HIV, etc.)424/228.1, Non-A, non-B hepatitis virus or hepatitis C virus424/227.1, Hepatitis B virus (e.g., hepatitis B surface antigen (HBsAg), pre-S region, hepatitis B core antigen (HBcAg), hepatitis B e-antigen, Dane particle, etc.)424/209.1Orthomyxoviridae (e.g., influenza virus, fowl plague virus, etc.)

Attorney, Agent or Firm

NOVARTIS VACCINES AND DIAGNOSTICS INC.

International Classes

A61K 9/14
A61K 39/21
A61K 39/29
A61K 39/145

Abstract text

The use of poly(lactide) or poly(lactide-co-glycolide) microparticles with adsorbed antigen is disclosed. The microparticles are useful for enhancing CTL responses to a selected antigen.

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