US Patent Application 20090324702 - NOVEL VIRAL VECTOR
Inventors
US Classes424/450, Liposomes435/320.1, VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.)435/239, Recovery or purification435/235.1, VIRUS OR BACTERIOPHAGE, EXCEPT FOR VIRAL VECTOR OR BACTERIOPHAGE VECTOR; COMPOSITION THEREOF; PREPARATION OR PURIFICATION THEREOF; PRODUCTION OF VIRAL SUBUNITS; MEDIA FOR PROPAGATING424/209.1, Orthomyxoviridae (e.g., influenza virus, fowl plague virus, etc.)424/199.1, Recombinant virus encoding one or more heterologous proteins or fragments thereof424/93.2Genetically modified micro-organism, cell, or virus (e.g., transformed, fused, hybrid, etc.)Attorney, Agent or FirmForeign Documents
International ClassesA61K 39/145C12N 15/00 C12N 7/02 C12N 7/00 A61K 35/76 A61K 9/127 Abstract textThe present invention provides a novel transfer vector and a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient, which are useful as preventive or therapeutic drugs for infectious diseases such as malaria and influenza; and methods for preventing and treating infectious diseases such as malaria and influenza. More specifically, the invention provides a recombinant transfer vector capable of expressing a foreign gene fused to a virus gene under the control of a dual promoter; a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient; and methods for preventing and treating infectious diseases such as malaria and influenza comprising administrating the recombinant baculovirus to patients. |
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