US Patent Application 20090311798 - SE(R)RS DISPLACEMENT ASSAY
Inventors
AssigneeUS Classes436/171, Spectrum analysis (e.g., flame photometry, etc.)536/24.3, Probes for detection of specific nucleotide sequences or primers for the synthesis of DNA or RNA422/68.1, Means for analyzing liquid or solid sample422/82.05, Measuring optical property by using ultraviolet, infrared, or visible light422/82.08FluorescenceAttorney, Agent or FirmForeign Documents
International ClassesG01N 21/65C07H 21/00 G01N 21/01 G01N 21/64 Abstract textA detection method is described for detecting an analyte, in particular nucleic acids, in a sample using SE(R)RS, without the need for labeling of the analyte. The detection method is based on the displacement of a labeled surrogate target probe from a capture probe by the analyte in the sample. The present invention also provides a corresponding detection system, to a disposable cartridge for use in such a system, and to a combination of surrogate target probe and capture probe. |
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