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US Patent Application 20090291103 - QUALITY CONTROL METHODS FOR OIL-IN-WATER EMULSIONS CONTAINING SQUALENE

Application 20090291103 Filed on November 6, 2007. Published on November 26, 2009

Inventor

Assignee

US Classes

424/209.1, Orthomyxoviridae (e.g., influenza virus, fowl plague virus, etc.)424/283.1, Lipid or oil436/142Unsaturated (e.g., ethylene, diene, etc.)

Attorney, Agent or Firm

Foreign Documents

  • 0622282.2 GB 11/08/2006

International Classes

A61K 39/145
A61K 47/44
G01N 33/15
A61P 37/04


Abstract text


Measurements of the squalene content in oil-in-water emulsions can be used as a way of checking for problems during production. In particular, it has been found that a drop in squalene content can indicate that filtration problems occurred. Testing the squalene content in the final lots is easier than investigating the characteristics of the filter, and so a squalene assay simplifies the quality control of oil-in-water emulsions.

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