US Patent Application 20090263470 - Vaccine Compositions Comprising Virosomes and a Saponin Adjuvant
InventorsUS Classes424/450, Liposomes424/204.1, Virus or component thereof424/207.1, Retroviridae (e.g., feline leukemia virus, bovine leukemia virus, avian leukosis virus, equine infectious anemia virus, Rous sarcoma virus, HTLV-I, etc.)424/208.1, Immunodeficiency virus (e.g., HIV, etc.)424/228.1, Non-A, non-B hepatitis virus or hepatitis C virus424/218.1, Togaviridae or Flaviviridae, except hepatitis C virus (e.g., yellow fever virus, bovine viral diarrhea virus, dengue virus, equine viral arteritis virus, equine encephalitis virus, Japanese B encephalitis virus, Sindbis virus, flavivirus, etc.)424/212.1, Measles virus or mumps virus424/209.1Orthomyxoviridae (e.g., influenza virus, fowl plague virus, etc.)Attorney, Agent or FirmForeign Documents
International ClassesA61K 9/127A61K 39/12 A61K 39/21 A61K 39/29 A61K 39/193 A61K 39/165 A61K 39/145 Abstract textThis invention provides virosome preparations from an enveloped virus, in particular from influenza virus, containing from said virus, and a saponin adjuvant. In particular the invention provides a virosome preparation from influenza virus an influenza antigen a QS21, optionally with a sterol. The invention also provides vaccine compositions containing said virosome preparations, methods of preparing said virosome preparations and vaccine containing them. |
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