US Patent Application 20090220543 - Expression of Proteins in Plants
InventorsUS Classes424/209.1, Orthomyxoviridae (e.g., influenza virus, fowl plague virus, etc.)800/288, Nonplant protein is expressed from the polynucleotide800/298, Higher plant, seedling, plant seed, or plant part (i.e., angiosperms or gymnosperms)530/370, Plant proteins, e.g., derived from legumes, algae or lichens, etc.435/320.1, VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.)424/204.1Virus or component thereofAttorney, Agent or FirmForeign Documents
International ClassesA61K 39/145C12N 15/82 A01H 5/00 C12N 15/87 C07K 14/00 C12N 15/63 A61K 39/12 Abstract textThe invention relates to a method of producing a HPV polypeptides and/or an influenza virus H5 polypeptide in a plant comprising the steps of cloning a HPV gene; and/or an influenza virus H5 gene or nucleic acid encoding their functional equivalents into a vector adapted to target components present in the plant, infiltrating at least a portion of the plant with the vector or transforming plant tissue with the vector so as to transiently express the HPV polypeptides and/or an influenza virus H5 polypeptide, and/or to create a transgenic plant; and recovering the HPV polypeptides and/or an influenza virus H5 polypeptide expressed by the plant. The invention further relates to vectors, transgenic plants or parts thereof and the progeny of such plants used in or which come about as a result of the method. |
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