US Patent Application 20090082717 - Dermal micro-organs, methods and apparatuses for producing and using the same
Inventors
US Classes604/22, With means for cutting, scarifying, or vibrating (e.g., ultrasonic, etc.) tissue424/400, PREPARATIONS CHARACTERIZED BY SPECIAL PHYSICAL FORM435/1.1, DIFFERENTIATED TISSUE OR ORGAN OTHER THAN BLOOD, PER SE, OR DIFFERENTIATED TISSUE OR ORGAN MAINTAINING; COMPOSITION THEREFOR424/574, Adipose or epithelium424/423, Surgical implant or material435/29, Involving viable micro-organism606/131, Means for removal of skin or material therefrom600/301Via monitoring a plurality of physiological data, e.g., pulse and blood pressureAttorney, Agent or FirmInternational ClassesA61M 1/00A61K 9/00 A01N 1/02 A61K 35/12 A61B 5/00 A61F 2/00 C12Q 1/02 A61B 17/50 Issued Patent Number:8142990Abstract textEmbodiments of the present invention provide Dermal Micro-organs (DMOs), methods and apparatuses for producing the same. Some embodiments of the invention provide a DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived, having dimensions selected so as to allow passive diffusion of adequate nutrients and gases to cells of the DMO and diffusion of cellular waste out of the cells so as to minimize cellular toxicity and concomitant death due to insufficient nutrition and accumulation of waste in the DMO. Some embodiments of the invention provide methods and apparatuses for harvesting the DMO. An apparatus for harvesting the DMO may include, according to some exemplary embodiments, a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate the DMO from the skin-related tissue structure. Other embodiments are described and claimed. |
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